Journal: Journal of Pharmacy Research

Article Id: JPRS-P'Col-00001071
Title: Evaluation of Anxiolytic Activity in four selected species of Arisaema
Category: Pharmacology
Section: Research Article
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    Background: Arisaema is a large genus containing numerous species which are being used traditionally by the various tribes and communities for treatment of various ailments such as asthma bronchitis, cold, cough, laryngitis, ringworm, sores, boils, abscesses, as analgesic, antitumor, and pesticide agents. Arisaema cumbile for treating dementia and neurological symptoms. Arisaema flavum for tetanus, epilepsy, skin diseases and as insecticide. So taking into account traditional uses of genus, four species A. tortuosum, A. jacquemontii, A. concinuum and A. flavum are selected for evaluating antianxiety potential in species. Method: In the present investigation hydroalcoholic extracts of tubers are prepared. All the crude extracts are evaluated for antianxiety activity in mice using elevated plus maze and Y maze model of anxiety. Result and Discussion: Among all the extract A.concinuum and A. flavum exhibited significant antianxiety activity with respect to control as well as standard (diazepam 2mg/kg) while other extracts have also increased the time spent in open arms.Conclusion: From this study it can be concluded that arisaema species were found useful in treating or decreasing anxiety in animal models.

     

    Cite this article as:Hemlata Verma, VK Lal and KK Pant,Evaluation of Anxiolytic Activity in four selected species of Arisaema, Journal of Pharmacy Research 2015,9(8),569-572.

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    Author(s) Name:

    Hemlata Verma1*, VK Lal1 and KK Pant2

    Affiliation(s) Name:

    *Dept. of Pharmacy, Uttrakhand Technical University, Dehradun, (U.K.), India
    1 Lavanya Pharmacy Pvt, Lucknow, (U.P), India
    2 Dept. of Pharmacology ,Chhatrapati Shahuji Maharaj Medical University Lucknow, (U.P), India

    *Corresponding author.
    Hemlata Verma
    Dept. of Pharmacy,
    Uttrakhand Technical University,
    Dehradun, (U.K.), India  

    Received on:14-06-2015; Revised on: 16-07-2015; Accepted on: 23-08-2015

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    Author:

    Hemlata Verma1*, VK Lal1 and KK Pant2

    Title:Evaluation of Anxiolytic Activity in four selected species of Arisaema
    Journal:Journal of Pharmacy Research
    Vol(issue):9 (August)
    Year:2015
    Page No: (569-572)
  • Experimental Methods Keywords

    Methodology:Anxiolytic Activity
    Research Materials:Four selected species of Arisaema

Keywords

Antianxiety Elevated plus maze Y maze Arisaema tortuosum A. jacquemontii A. concinuum A. flavum

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