Journal: Journal of Pharmacy Research

Article Id: JPRS-P'Col-00001073
Title: Protective effect of Cardiospermum halicacabum against Cadmium toxicity induced oxidative damage and biomarker enzymes alterations in the Fresh water Crab, Paratelphusa hydrodromaus
Category: Pharmacology
Section: Research Article
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  • Abstract

    Cadmium is a heavy metal widely used in industrial processes, has been recognized to be a highly toxic and dangerous environmental pollutant. These excess amounts in addition to naturally occurring levels gradually build up to toxic levels causing damages to the biota of the aquatic ecosystem. The fresh water field crab, Paratelphusa hydrodromous is an important human food source in parts of South India.  Evaluation of the toxic effect of cadmium on the experimental crab for the LC50 value was carried out. Effect of cadmium on the oxidative damage and biomarkers antioxidant enzymes in the hepatopancreas was observed. Quantitative study of antioxidant enzymes GSH, GPx, ACP and ALP were undertaken, result and discussed in detail.

    Cite this article as:K. Pugazhendy, A. Revathi, Kadarkarai Murugan and Jiang-Shiou Hwang,Protective effect of Cardiospermum halicacabum against Cadmium toxicity induced oxidative damage and biomarker enzymes alterations in the Fresh water Crab, Paratelphusa hydrodromaus,Journal of Pharmacy Research 2015,9(5),337-342.

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    Author(s) Name:

    K. Pugazhendy1*, A. Revathi1, Kadarkarai Murugan2 and Jiang-Shiou Hwang3

    Affiliation(s) Name:

    1Department of Zoology, Annamalai University, Annamalainagar-608 002, India,
    2Department of Zoology, Bharathiar University, Coimbatore- 641 029, India,
    3Institute of Marine Biology, National Taiwan Ocean University, Keelung 202-24, Taiwan

    *Corresponding author.
    Dr. K. Pugazhendy
    Assistant Professor,
    Department of Zoology,  
    Annamalai University,  
    Tamilnadu, India.

    Received on:25-03-2015; Revised on: 12-04-2015 ; Accepted on:02-06-2015

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    Author:

    K. Pugazhendy1*, A. Revathi1, Kadarkarai Murugan2 and Jiang-Shiou Hwang3

    Title:Protective effect of Cardiospermum halicacabum against Cadmium toxicity induced oxidative damage and biomarker enzymes alterations in the Fresh water Crab, Paratelphusa hydrodromaus
    Journal:Journal of Pharmacy Research
    Vol(issue):9 (May)
    Year:2015
    Page No: (337-342)
  • Experimental Methods Keywords

    Methodology:Cadmium, GSH, GPx, ACP and ALP, Toxicity.
    Research Materials:Cardiospermum halicacabum

Keywords

Hepatopancreas C.halicacabum Cadmium GSH GPx ACP and ALP Paratelphusa hydrodromaus Toxicity.

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