Journal: JPR:BioMedRx:An International Journal

Article Id: JPRS-DVD-00001079
Title: Preparation and Characterization of Pharmaceutical Grade Chitosan And Hydrated Chitosan Gums for Topical Preparations
Category: Development and Validation of Drugs
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  • Abstract

    The main goal of this work is the preparation and characterization of hydrated gums using chitosan for further formulation and topic applications. To achieve this goal several gums from pharmaceutical quality chitosan of low (Mw= 72.180 g/mol) and medium. (Mw= 103.000 g/mol) molecular weight with a 4% w/w were employed. The prepared hydrated gums were characterized by infrared spectroscopy, scanning electron microscopy andreological analyses. The spectroscopic study shows no great difference between both gums and most of chitosan bands are exhibited. The rheological studies shows that both gums exhibit a non Newtonian flow independent of the time, with pseudoplastic for low molecular weight chitosan and plastic behavior for the medium molecular weight.

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  • About the authors and Affiliations

    Author(s) Name:

    K.M. Dev Raj 1, J. Yamini2

    Affiliation(s) Name:

    Managing Director, Innomono Laboratories Private Limited, India
    Dept. of Chemistry, Vishnu Inst. of Pharmaceutical Education & Research, A.P, India

    *Corresponding author.
    K.M.DevRaj,
    Innomono Laboratories,
    #70, Road.no.36,
    Jubliee Hills,
    Hyderabad-81,Andhra Pradesh,India


    Received on:16-07-2013; Revised on:14-08-2013; Accepted on:19-09-2013

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    Author:

    K.M. Dev Raj 1, J. Yamini2

    Title:Preparation and Characterization of Pharmaceutical Grade Chitosan And Hydrated Chitosan Gums for Topical Preparations
    Journal:JPR:BioMedRx:An International Journal
    Vol(issue):1 (September)
    Year:2013
    Page No: (858-860)
  • Experimental Methods Keywords

    Methodology:Preparation and Characterization
    Research Materials:Hydrated gums

Keywords

Hydrated gums Chitosan Chitin Pseudoplastic Rheologic.

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