Journal: Inter. J. of Chemical and Analytical Science

Article Id: JPRS-AC-00001101
Title: Spectrophotometric Estimation of Ranolazine in Bulk and Pharmaceutical Dosage Form by UV- Specrtophotometry
Category: Analytical Chemistry
Section: Research Article
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    The present study describes a simple, accurate, precise and cost effective UV-VIS Spectrophotometric method for the estimation of Ranolazine (RZ), an anti-anginal drug, in bulk and pharmaceutical dosage form. The solvent used was distilled water and the λ max or the absorption maxima of the drug was found to be 272nm. A linear response was observed in the range of 20-100μg/ml with a correlation coefficient of 0.9998. The method was then validated for different parameters as per the ICH [2] (International Conference for Harmonization) guidelines. This method can be used for the determination of RZ in quality control of formulation without interference of the excipient.

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    Author(s) Name:

    Divyesh J Vanparia, Rajanikant M Chodavadia*, Prashant B Patel, Naresh M Kalsaria, Bhavin P Marolia, Shailesh A Shah

    Affiliation(s) Name:

    Department of Quality Assurance, Maliba Pharmacy College, Bardoli-Mahuva Road, Tarsadi, Dist. Surat, 394 350, Gujarat, India

    Corresponding Author:
    Rajanikant M Chodavadia, Department of Quality Assurance, Maliba Pharmacy College, Bardoli-Mahuva Road, Tarsadi, Dist. Surat, 394 350, Gujarat, India
    Received 17-06-2011; Accepted 22-08-2011

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    Author:

    Divyesh J Vanparia, Rajanikant M Chodavadia*, Prashant B Patel, Naresh M Kalsaria, Bhavin P Marolia, Shailesh A Shah

    Title:Spectrophotometric Estimation of Ranolazine in Bulk and Pharmaceutical Dosage Form by UV- Specrtophotometry
    Journal:Inter. J. of Chemical and Analytical Science
    Vol(issue):2 (September)
    Year:2011
    Page No: (1150-1152)
  • Experimental Methods Keywords

    Methodology:Spectrophotometric Estimation
    Research Materials:Ranolazine

Keywords

Ranolazine (RZ) λ max ICH UV-VIS spectroscopy.

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