Journal: Journal of Pharmacy Research

Article Id: JPRS-PC-00001103
Title: Stereo Selective Total Synthesis of Phomonol
Category: Pharmaceutical Chemistry
Section: Research Article
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  • Abstract

    A new stereo selective method has been described for the total synthesis of phomonol from optically active L-(-) diisopropyl tartarate (L-(-) DIPT). The sequence of synthesis includes Swern oxidation, Mac-Millan, Grignard and Oxa-Michael addition reactions as key steps in achieving the target molecule.

     

    Cite this article as: Bhaskar. K , Paramesh Jangili and A. Jaya Shree, Stereo Selective Total Synthesis of Phomonol,Journal of Pharmacy Research 2015,9(8),550-555.

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    Author(s) Name:

    Bhaskar. Ka ,  Paramesh Jangilib and A. Jaya Shree*,a

    Affiliation(s) Name:

    aCentre for Chemical Sciences and Technology, Institute of Science and Technology,
    Jawaharlal Nehru Technological University Hyderabad, Telangana-500 085. India.
    bNatural Products Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500607, India

    *Corresponding author.
    Prof. Jaya Shree Anireddy
    Centre for Chemical Sciences & Technology,
    Institute of Science & Technology,
    Jawaharlal Nehru Technological University Hyderabad,
    Kukatpally, Telangana-500 085. India.


    Received on:22-06-2015; Revised  on:  10-07-2015; Accepted on: 18-08-2015   

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    Author:

    Bhaskar. Ka ,  Paramesh Jangilib and A. Jaya Shree*,a

    Title:Stereo Selective Total Synthesis of Phomonol
    Journal:Journal of Pharmacy Research
    Vol(issue):9 (August)
    Year:2015
    Page No: (550-555)
  • Experimental Methods Keywords

    Methodology: Wittig olefination, Mac-Millan reaction, Grignard reaction, Oxa-Michael addition
    Research Materials:Phomonol

Keywords

Phomonol Swern oxidation Wittig olefination Mac-Millan reaction Grignard reaction Oxa-Michael addition

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