Journal: Inter. J. of Chemical and Analytical Science

Article Id: JPRS-PSPA-00001157
Title: Antihyperglycemic activity of Boerhaavia diffusa in streptozotocin induced diabetic rats
Category: Phytochemical Study and Pharmacological Activity
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  • Abstract

    Background: Many Indian medicinal plants were investigated in streptozotocin induced diabetic rat model and provided scientific validation to prove their antihyperglycemic activity. In view of alleged antidiabetic potential, effect of the aqueous and methanol extracts of Boerhaavia diffusa (Nyctaginaceae) roots, was observed on fasting blood sugar levels in streptozotocin induced diabetic rats. Methods: Fasting plasma glucose levels were determined by an enzymatic method using a kit. Results: Results show that both the extracts significantly reduced the blood glucose level in STZ induced diabetic rats. Conclusion: A plausible mechanism of action is that the extracts might have stimulated the residual pancreatic beta-cell function or produced the hypoglycaemia.

    Cite this article as: Deepti Malhotra, Fouzia Ishaq and Amir Khan,Antihyperglycemic activity of Boerhaavia diffusa in streptozotocin induced diabetic rats,International Journal of Chemical and Analytical Science 2014,5(1),21-23.

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    Author(s) Name:

    Deepti Malhotra1, Fouzia2 ,Ishaq and Amir Khan3*

    Affiliation(s) Name:

    1Department of Biotechnology, Shri Guru Ram Rai (P.G.) College, Dehradun (Uttarakhand) INDIA.
    2Limnological Research Lab. Deptt. of Zoology and Environmental Science, Gurukula Kangri University, Haridwar, UK, India.
    *3Glocal School of Life Science,The Glocal University (GU), Ali Akbarpur, Mirzapur Pol Saharanpur, 247001, (UP) India

    Corresponding author:
    Dr.Amir Khan
    *3 Glocal School of Life Science,
    The Glocal University (GU),
    Ali Akbarpur, Mirzapur Pol
    Saharanpur, 247001, (UP) India

    Received on: 15-11-2013; Revised on: 18-11-2013; Accepted on:21-12-2013

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    Author:

    Deepti Malhotra1, Fouzia2 ,Ishaq and Amir Khan3*

    Title:Antihyperglycemic activity of Boerhaavia diffusa in streptozotocin induced diabetic rats
    Journal:Inter. J. of Chemical and Analytical Science
    Vol(issue):6(1)
    Year:2015
    Page No: (21-23)
  • Experimental Methods Keywords

    Methodology:Antihyperglycemic activity, Fasting plasma glucose levels
    Research Materials:Boerhaavia diffusa

Keywords

Antihyperglycemic activity Boerhaavia diffusa Streptozotocin.

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