Journal: Journal of Pharmacy Research

Article Id: JPRS-ND-00001177
Title: Influence of solvent extraction on phenolic content, antioxidant and anti-inflammatory activities of aerial parts extract from Algerian Artemisia Herba-alba
Category: Natural Drugs
Section: Research Article
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    Artemisia Herba-alba is a commonly consumed medicinal and culinary herb in Algeria. This current study aimed to obtain the proper solvent for extracting bioactive compounds from Artemisa Herba-alba guided by phenolic content, flavonoid content, proanthocyanidins, antioxidant and anti-inflammatory activity. The results showed that ethyl acetate extract of exhibited the highest phytochemical composition (total phenolic content 92.29±3.25 mg GAE/g W, total flavonoids content 61.24±2.04 mg RT/g DW and proanthocyanidins 25.47±0.95 mg CAE/g DW), while butanol extract (BE), water extract (WE) and the minimum value in chloroform extract (CE). The best DPPH. scavenging capacity (IC50= 36.85±1.17 µm/mL), beta-carotene (23.83± 0.53) and ferric reducing power (IC50= 14.71± 0.51 µm/mL) were observed in EAE followed by BE. Our study also revealed the high anti-inflammatory potential of EAE, BE, WE and CE. Ethyl acetate can be an efficient solvent for extracting antioxidants from Artemisa Herba-alba based on this study. All these biological activities are well correlated with the phenolic contents of these extracts. These findings demonstrate the remarkable potential of these plants as valuable source of antioxidants with exhibit original and interesting anti-inflammatory and anticancer capacities.

    Cite this article as:Laouini S Eddine, Ouahrani M Redha, Segni Ladjel,Influence of solvent extraction on phenolic content, antioxidant and anti-inflammatory activities of aerial parts extract from Algerian Artemisia Herba-alba,Journal of Pharmacy Research 2016,10(1),58-64.

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    Author(s) Name:

    Laouini S Eddine1, Ouahrani M Redha1, Segni Ladjel2

    Affiliation(s) Name:

    1laboratory of Valorization and Technology of Saharian resources, Echahid Hamma Lakhdar University, PB 789,39000 El-Oued, Algeria
    2Process engineering Laboratory, Kasdi Merbah University, 30000 Ouargla, Algeria

    *Corresponding author.
    Dr. Laouini Salah Eddine,
    Valorisation and Technology of
    Resource Saharian Laboratory,
    El-Oued University, P.O. Box 789,
    El-Oued, Algeria.

    Received on:23-10-2015; Revised on: 27-12-2015; Accepted on: 14-01-2016

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    Author:

    Laouini S Eddine1, Ouahrani M Redha1, Segni Ladjel2

    Title:Influence of solvent extraction on phenolic content, antioxidant and anti-inflammatory activities of aerial parts extract from Algerian Artemisia Herba-alba
    Journal:Journal of Pharmacy Research
    Vol(issue):10 (January)
    Year:2016
    Page No: (58-64)
  • Experimental Methods Keywords

    Methodology:phytochemical, antioxidant, anti-inflammatory
    Research Materials:Artemisia Herba-alba

Keywords

Artemisia Herba-alba phytochemical antioxidant anti-inflammatory Algeria

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