Journal: Journal of Pharmacy Research

Article Id: JPRS-PHDRS-0000119
Title: anti-fertility activity and lipid peroxidatation effects of Clerodendrum serratum in male rats
Category: Pharmacognosy and Herbal Drugs related study
Section: Research Article
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    Aim:The objective of the present study is to explore anti-fertility and lipid peroxidation properties of methanolic extract of Clerodendrum Serratum aerial plant. Methods:The different dose of methanolic extracts were given by gavage to rats in the In Vivo test at a dose of 100, 300, 500mg/kg of body weight to rats in group II, II & III respectively, along with control dose. At the end of study various parameter such as biochemical and testicular lipid peroxidation levelwere analyzed. Result:Finding of this study explored a significantly decrease (p<0.05) the Alanine amino transferase, Aspartate aminotransferase and Alkaline phosphatase levels in methanolic extract of Clerodendrum Serratum treated rats when compared to control. But Malondialdehyde levels were significantly increased in methanolic extract of Clerodendrum Serratum treated rats testicular tissues in dose dependent manner when compared with control. Conclusion:The present study, it concluded that methanolic extract of Clerodendrum Serratum aerial parts have antifertility effects in male rats.

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    Author(s) Name:

    Sarath Chandiran Irisappan1, B. Kadalmani2, S. Navaneethakrishnan3*

    Affiliation(s) Name:

    1Professor& Principal, Gokula Krishna College of Pharmacy, Sullurpet-524121, Nellore dist, A.P, India.
    2Asst Professor, Department of Animal Science, Bharathidasan University, Tiruchirapalli 620024,Tamil Nadu, India
    3Research Scholar, Department of Pharmacology, PRIST University,Thanjavur- 613403,Tamil Nadu,India


    *Corresponding author.
    S. Navaneethakrishnan
    Research Scholar,
    Department of Pharmacology,
    PRIST University,
    Thanjavur- 613403,
    Tamil Nadu,India
    Email: nasveen@gmail.com


    Received on:22-11-2013; Revised on: 09-12-2013; Accepted on:12-01-2014

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    Author:

    Sarath Chandiran Irisappan1, B. Kadalmani2, S. Navaneethakrishnan3*

    Title:anti-fertility activity and lipid peroxidatation effects of Clerodendrum serratum in male rats
    Journal:Journal of Pharmacy Research
    Vol(issue):8 (February)
    Year:2014
    Page No: (174-178)
  • Experimental Methods Keywords

    Methodology:biochemical and testicular lipid peroxidation level analysis
    Research Materials:Clerodendrum Serratum

Keywords

Anti fertility Clerodendrum Serratum Malondialdehyde.

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