Journal: Journal of Pharmacy Research

Article Id: JPRS-PC-00001223
Title: Validated UV-Spectrophotometric Determination of Velathamate Bromide in Pure and Pharmaceutical Formulation
Category: Pharmaceutical Chemistry
Section: Research Article
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    Aim: The present work is aim to develop simple, extraction free and UV spectrophotometric method for the quantitative estimation of valethamate bromide in bulk drug and pharmaceutical formulations. Method: A simple double beam UV spectrophotometric method has been developed and validated with different parameters according to ICH guidelines. Results and discussion: The drug showed strong absorption at 227 nm and linearity in the concentration range of 50-300 μg/ml. Recovery studies for valethamate bromide was found to be 99.9%. The % RSD values were found to be within the range and found not interference from excipients and the proposed method was statistically validated. Conclusion: The results showed that the proposed method is suitable for the precise, accurate and rapid determination of valethamate bromide in bulk drug and its formulations.

    Cite this article as:Meghana. G.S, Gurupadayya B.M. Sowmya. S and Vasavi.T.N, Validated UV-Spectrophotometric Determination of Velathamate Bromide in Pure and Pharmaceutical Formulation,Journal of Pharmacy Research 2016,10(3),133-135.

     

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    Author(s) Name:

    Meghana. G.S, Gurupadayya B.M*. Sowmya. S and Vasavi.T.N

    Affiliation(s) Name:

    Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS University, Mysore – 570 015, Karnataka, India

    *Corresponding author.
    Dr. B.M.Gurupadayya
    Professor,
    Pharmaceutical Analysis Group,
    Dept. of Pharmaceutical Chemistry,
    J S S College of Pharmacy, J S S University,
    Shivarathreeshwara Nagar,
    Mysuru-570 015, Karnataka, India.

    Received on:14-01-2016; Revised on: 26-02-2016; Accepted on: 09-03-2016

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    Author:

    Meghana. G.S, Gurupadayya B.M*. Sowmya. S and Vasavi.T.N

    Title:Validated UV-Spectrophotometric Determination of Velathamate Bromide in Pure and Pharmaceutical Formulation
    Journal:Journal of Pharmacy Research
    Vol(issue):10 (March)
    Year:2016
    Page No: (133-135)
  • Experimental Methods Keywords

    Methodology:UV method, Analytical method, Validation
    Research Materials:Valethamate bromide

Keywords

Valethamate bromide UV method Analytical method Validation

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