Journal: Journal of Pharmacy Research

Article Id: JPRS-PC-00001332
Title: Heterocyclic 1, 3, 4-oxadiazole compounds with diverse biological activities: A comprehensive review
Category: Pharmaceutical Chemistry
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  • Abstract

    The chemistry of heterocyclic compounds has been an interesting field of study for a long time. Heterocyclic nucleus 1,3,4-oxadiazole constitutes an important class of compounds for new drug development. The synthesis of novel oxadiazole derivatives and investigation of their chemical and biological behavior have gained more importance in recent decades. Oxadiazole compounds possess an extensive spectrum of pharmacological activities. In particular, compounds bearing 1,3,4-oxadiazole nucleus are known to exhibit unique antiinflammatory, analgesic, antimicrobial, antitumor, anticonvulsant, anthelmintic, antimycobacterial, herbicidal, antioxidant and antiviral activities. Therefore, many researchers have synthesized these compounds as target structures and evaluated their biological activities. These observations have been guiding for the development of new oxadiazole derivatives that possess varied biological activities and can be a lead nucleus for future developments to get safer and effective compounds. References of the most relevant literature published by various research groups around the world are provided.

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  • About the authors and Affiliations

    Author(s) Name:

    Suman Bala,* Sunil Kamboj and Ashok Kumar

    Affiliation(s) Name:

    M. M. College of Pharmacy, Maharishi Markandeshwar University, Mullana, Ambala, Haryana

    *Corresponding author.
    Suman Bala,
    MM College of Pharmacy,
    MM University, Mullana,
    Ambala, Haryana, INDIA -133203.

     
    Received on: 15-06-2010; Revised on: 18-08-2010; Accepted on:13-09-2010

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    Author:

    Suman Bala,* Sunil Kamboj and Ashok Kumar

    Title:Heterocyclic 1, 3, 4-oxadiazole compounds with diverse biological activities: A comprehensive review
    Journal:Journal of Pharmacy Research
    Vol(issue):3(12)
    Year:2010
    Page No: (2993-2997)
  • Experimental Methods Keywords

    Methodology:biological activity
    Research Materials:Heterocycles, 1,3,4-oxadiazole

Keywords

Heterocycles 1 3 4-oxadiazole biological activity

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