Journal: Journal of Pharmacy Research

Article Id: JPRS-PC-00001337
Title: In-Vitro Anti-Inflammatory Activity of 2-Amino-3-(Substituted Benzylidinecarbohydrazide)-4,5,6,7-Tetrahydrobenzothiophenes.
Category: Pharmaceutical Chemistry
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  • Abstract

    In the present study, a new series of 2-Amino-3-(Substituted Benzylidinecarbohydrazide) -4,5,6,7-Tetrahydrobenzothiophenes (II a-i) were synthesized and screened for anti-inflammatory activity by in-vitro method. The structure of the compounds was characterized by IR spectral study and elemental analysis. Compound 2-amino-4,5,6,7-tetrahydrobenzothiophen-3-furylidinecarbo hydrazide (II i) showed significant anti-inflammatory activity. From this study, data revealed that carbohydrazide group is necessary for the potential activity.

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    Author(s) Name:

    *Jagtap V. A., Agasimundin Y. S.1, Jayachandran E.1 and Sathe B. S.

    Affiliation(s) Name:

    *Department of Pharmaceutical Chemistry, Smt. S. S. Patil College of Pharmacy, Chopda – 425 107 (M.S.) India
    1 P. G. Department of Pharmaceutical Chemistry, S. C. S. College of Pharmacy, Harapanahalli – 583 131 (K.S.) India

    *Corresponding author.
    Mr. Jagtap Vijay A.,
    Dept. of Pharmaceutical Chemistry,
    Smt. S. S. Patil College of Pharmacy, Chopda – 425 107
    Dist: Jalgaon (Maharashtra State),India

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    Author:

    *Jagtap V. A., Agasimundin Y. S.1, Jayachandran E.1 and Sathe B. S.

    Title:In-Vitro Anti-Inflammatory Activity of 2-Amino-3-(Substituted Benzylidinecarbohydrazide)-4,5,6,7-Tetrahydrobenzothiophenes.
    Journal:Journal of Pharmacy Research
    Vol(issue):4 (February)
    Year:2011
    Page No: (378-379)
  • Experimental Methods Keywords

    Methodology: In-vitro Anti-inflammatory activity.
    Research Materials:Carbohydrazides, Tetrahydrobenzothiophene,

Keywords

Carbohydrazides Tetrahydrobenzothiophene In-vitro Anti-inflammatory activity.

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