Journal: Journal of Pharmacy Research

Article Id: JPRS-P'Col-00001365
Title: Free Radicals and Antioxidants : A Review
Category: Pharmacology
Section: Review Article
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  • Abstract

    Oxidation is a significant biological process for energy production in the body. One of the crucial problem is the tendency of the oxygen molecule to create free radicals. These radicals are by-products of the natural metabolism, and their constant exposure can give rise to oxidative stress which causes the oxidation of proteins, lipids and nucleic acids. The release of reactive oxygen, nitrogen and sulphur species results in cellular damage, gene mutation, organ malfunctioning or organ failure and may even lead to death. This oxidative damage has a significant role in chronic diseases like cancer, diabetes, rheumatoid arthritis, AIDS, nephropathy,neurodegenerative and reproductive disorders, pulmonary and cardiovascular diseases etc. If our body’s supply of antioxidants fall short from the free radical generation, then its possible that it could cause damage before the radicals are quenched. This review deals with the types of free radicals, their role in various disease, antioxidants and the different constituents which show antioxidant activity.

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    Author(s) Name:

    Blessy Baby Mathew*, Archana Tiwari, Suresh Kumar Jatawa

    Affiliation(s) Name:

    School of Biotechnology, Rajiv Gandhi Technological University, Gandhi Nagar, Bhopal-36, M.P.

    *Corresponding author.
    Blessy Baby Mathew
    School of Biotechnology,
    Rajiv Gandhi Technological University,
    Gandhi Nagar, Bhopal-36, M.P.


    Received on:22-08-2011; Revised on: 15-09-2011; Accepted on:11-11-2011

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    Author:

    Blessy Baby Mathew*, Archana Tiwari, Suresh Kumar Jatawa

    Title:Free Radicals and Antioxidants : A Review
    Journal:Journal of Pharmacy Research
    Vol(issue):4 (December)
    Year:2011
    Page No: (4340-4343)
  • Experimental Methods Keywords

    Methodology:Reactive oxygen species, Reactive nitrogen species, Reactive sulfur species, Oxidative stress.
    Research Materials:Free Radical

Keywords

Reactive oxygen species Reactive nitrogen species Reactive sulfur species Oxidative stress.

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