Article Id:JPRS-MB-00001378 Title:A comparative study of antimicrobial potential and phytochemical analysis of Artocarpus heterophyllus and Manilkara zapota seed extracts Category:Microbiology Section:Research Article
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The present study was undertaken to describe the comparative evaluation of phytochemical constituents and antimicrobial activity of Artocarpus heterophyllus and Manilkara zapota seeds in four different solvents. A preliminary phytochemical analysis was carried out and concluded that the presence of alkaloids, tannins, phenolic compounds, flavonoids and saponins in both extract. The antimicrobial activity was tested using agar well diffusion method against six bacterial and four fungal strains and whereas, gentamycin and chloramphenical as antibiotic standards. The results showed that the antibacterial and antifungal activities were effective in ethanol, acetone and aqueous fractions of seed extract than ethyl acetate fractions in both samples. The MIC was determined in four different solvents of both extracts and reported that ethanol, acetone and aqueous extract possess minimum inhibition in both extract than ethylacetate. From the present study, it can be concluded that Artocarpus heterophyllus and Manilkara zapota seed extracts has effective antimicrobial activity and potent phytochemical constituents.
K.Shanmugapriya1*, P.S.Saravana2, Harsha Payal2, S. Peer Mohammed2, Williams Bennai2,
Affiliation(s) Name:
1 Assistant Professor, School of Biotechnology, Dr.G.R.Damodaran College of Science, Coimbatore-641014,Tamil Nadu, India. 2 School of Biotechnology, Dr.G.R.Damodaran College of Science, Coimbatore-641014, Tamil Nadu, India.
*Corresponding author. K.Shanmugapriya, Assistant professor, School of Biotechnology, Dr.G.R.Damodaran College of Science, Coimbatore-641014, Tamil Nadu, India.
Received on: 14-05-2011; Revised on: 15-06-2011; Accepted on:09-07-2011