Journal: Journal of Pharmacy Research

Article Id: JPRS-PCS-00001394
Title: RP-HPLC method for simultaneous estimation of Atorvastatin Calcium and Fenofibrate in tablet dosage forms
Category: Pharmaceutics
  • Abstract
  • Audio Abstract
  • Authors
  • Pdf File
  • Citation
  • My Reference
  • Methodology
  • Abstract

    A reverse phase high performance liquid chromatographic method was developed for simultaneous estimation of atorvastatin calcium and fenofibarte in tabletformulation. The separation was achieved by HiQ sil C-8 (4.6×250mm) column with a mobile phase consisting of methanol: water pH 3.2 (90:10v/v), at a flow rateof 1ml/min. Detection was carried out at 260 nm. Retention time of atorvastatin calcium and fenofibrate was found to be 3.32 and 4.51 min, respectively. The method has been validated for linearity, accuracy and precision. Developed method was found to be accurate, precise, selective and rapid for simultaneous estimation of atorvastatin calcium and fenofibrate in tablets.

  • Abstract Audio

    Click Here

  • About the authors and Affiliations

    Author(s) Name:

    Rupali Hirave,* Ravindra Bendagude 1 , Manish Kondawar.

    Affiliation(s) Name:

    Aapasaheb birnale College of Pharmacy, South Shivajinagar, Sangli. 416416(MS),1SVERI’S College of Pharmacy, Pandharpur.

    *Corresponding author.
    Rupali Hirave*
    Appasaheb Birnale College of Pharmacy,
    Sangli, Maharashtra, India-416416

    Received on: 08-06-2010; Revised on: 22-07-2010; Accepted on:12-09-2010

  • View Article File in pdf format.

    Article File
  • View Article Citation Here.

    7 View More
  • How to Cite my Article.

    Author:

    Rupali Hirave,* Ravindra Bendagude 1 , Manish Kondawar.

    Title:RP-HPLC method for simultaneous estimation of Atorvastatin Calcium and Fenofibrate in tablet dosage forms
    Journal:Journal of Pharmacy Research
    Vol(issue):3(10)
    Year:2010
    Page No: (2400-2401)
  • Experimental Methods Keywords

    Methodology:RP-HPLC method
    Research Materials: atorvastatin calcium , fenofibrate

Keywords

RP-HPLC simultaneous determination atorvastatin calcium fenofibrate development and validation.

Our Services

Most Downloaded List