Journal: Journal of Pharmacy Research
Title: In-vitro antioxidant and antibacterial activities of different fractions of Heliotropium indicum L.
Category: Pharmacognosy and Herbal Drugs related study
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Abstract
In this study we investigated the In-vitro Antioxidant (DPPH radical) and Antibacterial activity of different fractions (hydro-alcoholic, methanolic, ethyl acetate and hexane) of Heliotropium indicum was carried out against nine selected pathogenic bacteria. In preliminary phytochemical investigation of the plant extracts, quantified the total phenolic content by taking Gallic acid as a standard, In-vitro antibacterial activity was evaluated for extracts by using cup plate method and In-vitro antioxidant activity by using DPPH free radical. In preliminary phytochemical investigation the plant extracts possesses Steroids, terpenoids, Saponins, Flavonoids, Carbohydrates, Glycosides, Amino acids and oils .Among the selected extracts ethyl acetate fraction of H.indicum showed high phenolic content and same fraction was showed more DPPH radical scavenging activity . For antibacterial activity, Ethyl acetate fraction showed good antibacterial activity against all the tested bacteria except Priteus mirabilis, Salmonella typhimurium. The antibacterial activity was may be due to phenolic compounds present in the extracts. In the present study we found that the different fractions of Heliotropium indicum showed good Antioxidant and Antibacterial activity.
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About the authors and Affiliations
Author(s) Name: Rajeswara Rao Pragada1, Sambasiva Rao Ethadi*, 1, Yasodhara.B2, V.S.Praneeth.Dasari1, Mallikarjuna Rao.T1
Affiliation(s) Name: 1A.U College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, A.P, India-530003
2Department of Biotechnology, Andhra University, Visakhapatnam, A.P, India-530003*Corresponding author.
Sambasiva Rao Ethadi M.Pharm, (Ph.D).
A.U College of Pharmaceutical Sciences, Andhra University,
Visakhapatnam,
A.P, India-530 003.Received on:10-11-2011; Revised on: 15-12-2011; Accepted on:12-01-2012
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Author: Rajeswara Rao Pragada1, Sambasiva Rao Ethadi*, 1, Yasodhara.B2, V.S.Praneeth.Dasari1, Mallikarjuna Rao.T1
Title: In-vitro antioxidant and antibacterial activities of different fractions of Heliotropium indicum L. Journal: Journal of Pharmacy Research Vol(issue): 5(2) Year: 2012 Page No: (1051-1053) -
Experimental Methods Keywords
Methodology: DPPH radical, Total Phenolic content, In-vitro Antibacterial activity, In-vitro Antioxidant Activity. Research Materials: Heliotropium indicum
Keywords
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