Journal: Journal of Pharmacy Research
Title: In-vitro antioxidant and antibacterial activities of different fractions of Heliotropium indicum L.
Category: Pharmacognosy and Herbal Drugs related study
Section: Research Article
- Abstract
- Audio Abstract
- Authors
- Pdf File
- Citation
- My Reference
- Methodology
-
Abstract
In this study we investigated the In-vitro Antioxidant (DPPH radical) and Antibacterial activity of different fractions (hydro-alcoholic, methanolic, ethyl acetate and hexane) of Heliotropium indicum was carried out against nine selected pathogenic bacteria. In preliminary phytochemical investigation of the plant extracts, quantified the total phenolic content by taking Gallic acid as a standard, In-vitro antibacterial activity was evaluated for extracts by using cup plate method and In-vitro antioxidant activity by using DPPH free radical. In preliminary phytochemical investigation the plant extracts possesses Steroids, terpenoids, Saponins, Flavonoids, Carbohydrates, Glycosides, Amino acids and oils .Among the selected extracts ethyl acetate fraction of H.indicum showed high phenolic content and same fraction was showed more DPPH radical scavenging activity . For antibacterial activity, Ethyl acetate fraction showed good antibacterial activity against all the tested bacteria except Priteus mirabilis, Salmonella typhimurium. The antibacterial activity was may be due to phenolic compounds present in the extracts. In the present study we found that the different fractions of Heliotropium indicum showed good Antioxidant and Antibacterial activity.
-
Abstract Audio
About the authors and Affiliations
Author(s) Name: Rajeswara Rao Pragada1, Sambasiva Rao Ethadi*, 1, Yasodhara.B2, V.S.Praneeth.Dasari1, Mallikarjuna Rao.T1
Affiliation(s) Name: 1A.U College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, A.P, India-530003
2Department of Biotechnology, Andhra University, Visakhapatnam, A.P, India-530003*Corresponding author.
Sambasiva Rao Ethadi M.Pharm, (Ph.D).
A.U College of Pharmaceutical Sciences, Andhra University,
Visakhapatnam,
A.P, India-530 003.Received on:10-11-2011; Revised on: 15-12-2011; Accepted on:12-01-2012
-
View Article File in pdf format.
Article File
-
View Article Citation Here.
9 View More -
How to Cite my Article.
Author: Rajeswara Rao Pragada1, Sambasiva Rao Ethadi*, 1, Yasodhara.B2, V.S.Praneeth.Dasari1, Mallikarjuna Rao.T1
Title: In-vitro antioxidant and antibacterial activities of different fractions of Heliotropium indicum L. Journal: Journal of Pharmacy Research Vol(issue): 5 (February) Year: 2012 Page No: (1051-1053) -
Experimental Methods Keywords
Methodology: DPPH radical, Total Phenolic content, In-vitro Antibacterial activity, In-vitro Antioxidant Activity. Research Materials: Heliotropium indicum
Keywords
Our Services
- Mucoadhesive oral in situ gel of itraconazole using pH-sensitive polymers: Preparation, and in vitro characterization, release and rheology study
- Pharmacognostic standardization and high-performance thin-layer chromatography fingerprint profile of Lagenaria siceraria (Molina) Standl. fruits
- Phytochemical and pharmacological potential of Artemisia absinthium Linn. and Artemisia asiatica Nakai : A Review
- Antibacterial activity of different endodontic sealers: An in vitro evaluation
- Effectiveness of good behavior game on oral health among children - A randomized trial
- Effect of music on academic performance of college students
- Medicinal uses of banana (Musa paradisiaca)
- Extraction of Betacyanin from Red Beet root (Beta vulgaris L.) and to evaluate its antioxidant potential antioxidant potential
- Biodegradable plastic production from corn starch
- Standardization of Nandhi Mezhugu, a poly herbomineral Siddha formulation
- The role of toponymic objects in the system of settlement and reconstruction of landscapes in the Pre-Volga Region of the Republic of Tatarstan
- Estimation of Tizanidine HCl by UV-Spectrophotometric Method
- Formulation and evaluation of topical gel of diclofenac sodium using different polymers
- Antidiabetic activity of insulin plant (Costus igneus) leaf extract in diabetic rats
- Effects of lupeol on insulin receptor and glucose transporter-4 in cardiac tissue of Type-2 diabetic rats
- Simultaneous Spectrophotometric Estimation of Paracetamol and Aceclofenac in Combined Tablet Formulations using Hydrotropic Solubilization Technique
- Benzoic acid, one of the major components of aqueous bark extract of Terminalia arjuna protects against Copper-Ascorbate induced oxidative stress in human placental mitochondria through antioxidant m
- Formulation and Evaluation of Sildenafil Citrate Fast Dissolving Tablets Using Crospovidone and Croscarmellose Sodium Superdisintegrants
- Ethosomes: A novel tool for drug delivery through the skin
- Validation of Uv Spectrophotometric method for estimation of Levocetirizine Dihydrochloride in bulk and pharmaceutical formulation
- Formulation and evaluation of solid dispersions of valsartan for dissolution rate enhancement
- In silico and in vivo approach to identify the antidiabetic activity of lupeol
- Comparative Study of Ionotropic Gelation Technique To Entrap Diltiazem HCl In Mucoadhesive Microparticulate System.
- Fomulation and Evaluation of Taste Masked Spherical Agglomerates of Telmisartan
- Preparation and Characterization of Pharmaceutical Grade Chitosan And Hydrated Chitosan Gums for Topical Preparations
- Assortment of vital nutrients for enhancement of Cyclodextrin glycosyltransferase produced by Bacillus amyloliquefaciens KST5: A Plackett-Burman design approach
- Aspergillus Derived Silver Nano Particles as a Potent Antibacterial Agent and Identification of Linked Proteins
- In vitro antibacterial activity of essential oils of selected herbals against isolates from HIV/AIDS patients
- Novel Controlled Gastroretentive Drug Delivery Systems: A Review
- Antiulcer activity of aqueous suspension of Saraca indica flower against gastric ulcers in albino rats