Journal: Journal of Pharmacy Research
Title: In-vitro antioxidant and antibacterial activities of different fractions of Heliotropium indicum L.
Category: Pharmacognosy and Herbal Drugs related study
- Abstract
- Audio Abstract
- Authors
- Pdf File
- Citation
- My Reference
- Methodology
-
Abstract
In this study we investigated the In-vitro Antioxidant (DPPH radical) and Antibacterial activity of different fractions (hydro-alcoholic, methanolic, ethyl acetate and hexane) of Heliotropium indicum was carried out against nine selected pathogenic bacteria. In preliminary phytochemical investigation of the plant extracts, quantified the total phenolic content by taking Gallic acid as a standard, In-vitro antibacterial activity was evaluated for extracts by using cup plate method and In-vitro antioxidant activity by using DPPH free radical. In preliminary phytochemical investigation the plant extracts possesses Steroids, terpenoids, Saponins, Flavonoids, Carbohydrates, Glycosides, Amino acids and oils .Among the selected extracts ethyl acetate fraction of H.indicum showed high phenolic content and same fraction was showed more DPPH radical scavenging activity . For antibacterial activity, Ethyl acetate fraction showed good antibacterial activity against all the tested bacteria except Priteus mirabilis, Salmonella typhimurium. The antibacterial activity was may be due to phenolic compounds present in the extracts. In the present study we found that the different fractions of Heliotropium indicum showed good Antioxidant and Antibacterial activity.
-
Abstract Audio
About the authors and Affiliations
Author(s) Name: Rajeswara Rao Pragada1, Sambasiva Rao Ethadi*, 1, Yasodhara.B2, V.S.Praneeth.Dasari1, Mallikarjuna Rao.T1
Affiliation(s) Name: 1A.U College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, A.P, India-530003
2Department of Biotechnology, Andhra University, Visakhapatnam, A.P, India-530003*Corresponding author.
Sambasiva Rao Ethadi M.Pharm, (Ph.D).
A.U College of Pharmaceutical Sciences, Andhra University,
Visakhapatnam,
A.P, India-530 003.Received on:10-11-2011; Revised on: 15-12-2011; Accepted on:12-01-2012
-
View Article File in pdf format.
Article File
-
View Article Citation Here.
9 View More -
How to Cite my Article.
Author: Rajeswara Rao Pragada1, Sambasiva Rao Ethadi*, 1, Yasodhara.B2, V.S.Praneeth.Dasari1, Mallikarjuna Rao.T1
Title: In-vitro antioxidant and antibacterial activities of different fractions of Heliotropium indicum L. Journal: Journal of Pharmacy Research Vol(issue): 5(2) Year: 2012 Page No: (1051-1053) -
Experimental Methods Keywords
Methodology: DPPH radical, Total Phenolic content, In-vitro Antibacterial activity, In-vitro Antioxidant Activity. Research Materials: Heliotropium indicum
Keywords
Our Services
- Solubility and Dissolution Enhancement: An overview
- Evaluation of Phenolic Content and Antioxidant Capacity of leaf extract from Phoenix Dactylifera L obtained by different pH of aqueous extraction
- Evaluation of Cardioprotective Role of Vinpocetine in Isoproterenol-induced Myocardial Infarction in Rats
- Benzoic acid, one of the major components of aqueous bark extract of Terminalia arjuna protects against Copper-Ascorbate induced oxidative stress in human placental mitochondria through antioxidant m
- Development and Validation of Stability Indicating UV Spectrophotometric Method for the Estimation of Sitagliptin Phosphate in Bulk and Tablet Dosage Form
- Biological synthesis of silver nanoparticles using aqueous leaf extract of Capparis decidua (FORSK.) EDGEW: A better alternative
- Standardization of Nandhi Mezhugu, a poly herbomineral Siddha formulation
- Study of health related quality of life in rheumatoid arthritis patients
- Zinc-silibinin complex ameliorates oxidative stress in high fat fed low dose STZ induced type 2 diabetes in rats
- Melatonin affords protection against myocardial ischemia-induced cerebral mitochondrial dysfunction: an in vivo study.
- Prescribing Patterns of antihypertensive drugs in a South Indian tertiary care hospital
- In vitro anti-Candida activity of Calotropis gigantea.
- In vitro antioxidant, anti-inflammatory and anticholinesterase activities of Rumex vesicarius L
- Antimicrobial activity of seaweeds Gracillaria, Padina and Sargassum sps. on clinical and phytopathogensSubba Rangaiah G, Lakshmi P* and Manjula E
- Gastroprotective effect of Fenugreek 4-hydroxyisoleucine and trigonelline enriched fraction (TF4H (28%)) Sugaheal® against indomethacin induced ulcer in male wistar rats.
- Anti ulcer activity of Naravelia zeylanica leaves extract
- Pharmacognostic, Phytochemical & Quantitative Investigation of Saraca asoca leaves
- Synthesis and Biological Activity of Novel Acyl Hydrazone Derivatives of 3-(4,5-diphenyl-1,3-oxazol-2-yl) propanoic acid as Anticancer, Analgesic and Anti-inflammatory Agents
- Design and Synthesis of Novel Quinazolinone Derivatives as Broad Spectrum Anticonvulsant and Antimicrobial Agent
- Triazole analogues as novel antioxidants: In vitro bioassay and molecular modeling studies
- Genome of Acinetobacter baumannii Carries Multi Drug Resistance Genes
- Effects of Osmolytes on The Structural Stability of Bovine Trypsin: A Brief Review
- In vitro antioxidant and ptp inhibitory activity of methanolic extract of Anogeissus acuminata leaf and bark.
- Formulation and evaluation of topical gel of diclofenac sodium using different polymers
- Anticonvulsant And Antioxidant Actions Of Some Dibenzo-a-Pyrone Derivatives In Pentylene –Induced Kindling Model In Mice
- In vitro Antioxidant Activity from Leaves of Oroxylum indicum (L.) Vent. -A North Indian Highly Threatened and Vulnerable Medicinal Plant
- FORMULATION AND IN VITRO EVALUATION OF NIOSOME ENCAPSULATED ACYCLOVIR
- Assessment of Pharmacognostical Characters of Leaves of Tephrosia Purpurea Linn
- Phytochemical Screening and Evaluation of Polyphenols, Flavonoids and Antioxidant Activity of Prunus cerasoides D. Don Leaves
- Formulation and Evaluation of Fast Dissolving Tablets of Ranitidine Hydrochloride