Journal: Journal of Pharmacy Research

Article Id: JPRS-PHDRS-00001479
Title: In-vitro antioxidant and antibacterial activities of different fractions of Heliotropium indicum L.
Category: Pharmacognosy and Herbal Drugs related study
Section: Research Article
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  • Abstract

     In this study we investigated the In-vitro Antioxidant (DPPH radical) and Antibacterial activity of different fractions (hydro-alcoholic, methanolic, ethyl acetate and hexane) of Heliotropium indicum was carried out against nine selected pathogenic bacteria. In preliminary phytochemical investigation of the plant extracts, quantified the total phenolic content by taking Gallic acid as a standard,  In-vitro antibacterial activity was evaluated for extracts by using cup plate method and In-vitro antioxidant activity by using DPPH free radical. In preliminary phytochemical investigation the plant extracts possesses Steroids, terpenoids, Saponins, Flavonoids, Carbohydrates, Glycosides, Amino acids and oils .Among the selected extracts ethyl acetate fraction of H.indicum showed high phenolic content and same fraction was showed more DPPH radical scavenging activity . For antibacterial activity, Ethyl acetate fraction showed good antibacterial activity against all the tested bacteria except Priteus mirabilis, Salmonella typhimurium. The antibacterial activity was may be due to phenolic compounds present in the extracts. In the present study we found that the different fractions of Heliotropium indicum showed good Antioxidant and Antibacterial activity.

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    Author(s) Name:

    Rajeswara Rao Pragada1, Sambasiva Rao Ethadi*, 1, Yasodhara.B2, V.S.Praneeth.Dasari1, Mallikarjuna Rao.T1

    Affiliation(s) Name:

    1A.U College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, A.P, India-530003
    2Department of Biotechnology, Andhra University, Visakhapatnam, A.P, India-530003

    *Corresponding author.
    Sambasiva Rao Ethadi M.Pharm, (Ph.D).
    A.U College of Pharmaceutical Sciences, Andhra University,
    Visakhapatnam,
     A.P, India-530 003.

    Received on:10-11-2011; Revised  on: 15-12-2011; Accepted on:12-01-2012

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    Author:

    Rajeswara Rao Pragada1, Sambasiva Rao Ethadi*, 1, Yasodhara.B2, V.S.Praneeth.Dasari1, Mallikarjuna Rao.T1

    Title:In-vitro antioxidant and antibacterial activities of different fractions of Heliotropium indicum L.
    Journal:Journal of Pharmacy Research
    Vol(issue):5 (February)
    Year:2012
    Page No: (1051-1053)

  • Experimental Methods Keywords

    Methodology:DPPH radical, Total Phenolic content, In-vitro Antibacterial activity, In-vitro Antioxidant Activity.
    Research Materials:Heliotropium indicum

Keywords

Heliotropium indicum DPPH radical Total Phenolic content In-vitro Antibacterial activity In-vitro Antioxidant Activity.

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