Journal: Journal of Pharmacy Research

Article Id: JPRS-PC-00001481
Title: Synthesis, characterization and antimicrobial activity of some thiophene derivatives.
Category: Pharmaceutical Chemistry
  • Abstract
  • Audio Abstract
  • Authors
  • Pdf File
  • Citation
  • My Reference
  • Methodology
  • Abstract

    We have synthesized a series of new thiophenes with various substitutions at 2-amino position[2]. The starting material 2-amino-3-carboxamido-4, 5, 6, 7-tetramethylene thiophene was synthesized as per literature method which were derivatised into Schiff bases by reacting with various substituted aromatic aldehydes. The synthesized new compounds were characterized by  mp, TLC, UV, IR, NMR and Mass spectrum. The synthesized compounds were screened for their antibacterial activity against two gram positive and two gram negative bacteria and antifungal screening against two fungi using Ampicillin and Miconazole nitrate.

  • Abstract Audio

    No Audio file found

  • About the authors and Affiliations

    Author(s) Name:

    Shanmugapriya Senthilkumaran*, Kalvikkarasi Shyamalavarnan,Korella Sravani,Velmurugan Vadivel,Vijey Aanandhi Muthukumar.

    Affiliation(s) Name:

    Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences,Vels University (VISTAS), Pallavaram-600117, Tamilnadu, India.

    *Corresponding author.
    S.Shanmugapriya.
    Department of Pharmaceutical Chemistry,
    School of Pharmaceutical Sciences,
    Vels University, (VISTAS),
    Pallavaram-600017,
    Tamilnadu, India.

    Received on:10-11-2011; Revised  on: 15-12-2011; Accepted on:12-01-2012

  • View Article File in pdf format.

    Article File
  • View Article Citation Here.

    3 View More
  • How to Cite my Article.

    Author:

    Shanmugapriya Senthilkumaran*, Kalvikkarasi Shyamalavarnan,Korella Sravani,Velmurugan Vadivel,Vijey Aanandhi Muthukumar.

    Title: Synthesis, characterization and antimicrobial activity of some thiophene derivatives.
    Journal:Journal of Pharmacy Research
    Vol(issue):5(2)
    Year:2012
    Page No: (1067-1069)
  • Experimental Methods Keywords

    Methodology:Synthesis, characterization , antimicrobial activity
    Research Materials:thiophene derivatives

Keywords

Schiff bases 2-amino-3-carboxamido-4 5 6 7-tetramethylene thiophene Antibacterial Antifungal Ampicillin and Miconazole nitrate

Our Services

Most Downloaded List