Journal: Journal of Pharmacy Research

Article Id: JPRS-PHDRS-000015
Title: Annona squamosa L.:Phytochemical analysis and Antimicrobial Screening
Category: Pharmacognosy and Herbal Drugs related study
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  • Abstract

    Four different solvent extracts of leaves of Custard apple (Annona squamosa L.) were studied for its antibacterial activity. Agar diffusion method was selected to check antibacterial activity, whereas phytochemical analysis was done by HPTLC instrument of Camag system. Two Gram positive (Staphylococcus aureus and Bacillus subtilis) and two Gram negative (Escherichia coli and Pseudomonas aeruginosa) bacteria were selected for screening. The screening results showed that highest zone of inhibition was observed in methanol extract against Ps. aeruginosa (MIC: 130μg/ml) followed by petroleum ether extract against Ps. aeruginosa (MIC: 165 μg/ml) and methanol extract against E. coli (MIC: 180 μg/ml). The present study demonstrates the presence of some phytochemicals (Linalool, Borneol, Eugenol, Farnesol, and Geraniol) in extracts which provide antibacterial activity.

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    Author(s) Name:

    Jayshree D. Patel1*and Vipin Kumar1 

    Affiliation(s) Name:


    1Sadbhav SRISTI Sansodhan Laboratory,SRISTI, Gujarat University Area, Near Vijay Chaar Rasta Navrangpura, Ahmedabad- 380 009 INDIA.


    * For correspondence:

    Jayshree D. Patel,

    Sadbhav SRISTI Sansodhan Laboratory,SRISTI, Gujarat University Area,
    Near Vijay Chaar Rasta Navrangpura, Ahmedabad-380 009 INDIA
    E-mail: jdpatels@gmail.com


    Received on: 02-05-2008; Accepted on :14-07-2008

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    Author:

    Jayshree D. Patel1*and Vipin Kumar1 

    Title:Annona squamosa L.:Phytochemical analysis and Antimicrobial Screening
    Journal:Journal of Pharmacy Research
    Vol(issue):1 (July-September 2008)
    Year:2008
    Page No: (34-38)
  • Experimental Methods Keywords

    Methodology:Antimicrobial, Phytochemical,HPTLC
    Research Materials:Annona squamosa L

Keywords

Antimicrobial Phytochemical Annona squamosa HPTLC

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