Journal: Journal of Pharmacy Research

Article Id: JPRS-PHDRS-000016
Title: Antidiabetic And Antihyperlipidaemic Effect of Alcoholic extract of Chlorophytum borivilianum Roots in Alloxan Induced Diabetic Albino Rats.
Category: Pharmacognosy and Herbal Drugs related study
Section: Research Article
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  • Abstract

    Chlorophytum borivilianum, commonly known as ‘safed musli’, is widely used in different parts of India for the treatment of diabetes mellitus. The present study was designed to evaluate the antidiabetic and antihyperlipidaemic effect of alcoholic extract of Chlorophytum borivilianum root (CREt) in alloxan induced diabetic rats. Diabetes was induced by single intraperitoneal injection of alloxan (150 mg/kg of body weight). Oral administration of alcoholic CREt to diabetic rats, at a dose of 100 mg/kg body weight, resulted in a significant reduction in blood glucose, urine sugar and serum lipids in alloxan diabetic rats. The extract also increases the total haemoglobin lever. The extract effect was similar to that of insulin. Thus, the investigation clearly shows that alcoholic CREt has both antidiabetic and antihyperlipidaemic effects.

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    Author(s) Name:

    Guno.Sindhu.Chakraborthy*1, Vidhu Aeri

    Affiliation(s) Name:

    1SVKM’S, NMiMS University, SPTM, Shirpur Campus, Maharashtra 425 405, India
    2 Department of Pharmacognosy and Phytochemistry, Hamdard University, New Delhi 110062, India


    For correspondence:

    G.S.Chakraborthy, SVKM’S, NMiMS University, SPTM, Shirpur Campus, Maharashtra
    425 405, India


    E-mail: phdgs77@indiatimes.com


    Received on: 08-05-2008; Accepted on :22-07-2008

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    Author:

    Guno.Sindhu.Chakraborthy*1, Vidhu Aeri

    Title:Antidiabetic And Antihyperlipidaemic Effect of Alcoholic extract of Chlorophytum borivilianum Roots in Alloxan Induced Diabetic Albino Rats.
    Journal:Journal of Pharmacy Research
    Vol(issue):1 (July-September 2008)
    Year:2008
    Page No: (29-33)
  • Experimental Methods Keywords

    Methodology:Antidiabetic And Antihyperlipidaemic Effect
    Research Materials:Chlorophytum borivilianum

Keywords

Chlorophytum borivilianum; alloxan diabetic; Antidiabetic; Antihyperlipidaemic

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