Journal: Journal of Pharmacy Research

Article Id: JPRS-PC-00001604
Title: Synthesis and Biological Evaluation of Some Novel Formazans
Category: Pharmaceutical Chemistry
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  • Abstract

    A series of novel 1-substituted phenyl-3-(4-nitrophenyl)-4-[benzamido-(2-methyl-3-quinazolin)-4-one] formazans (6a-h) have been synthesized from corresponding Schiff base (5) which was coupled with various aryl diazonium chloride in pyridine produced 1-substituted phenyl-3-(4-nitrophenyl)-4-[benzamido-(2-methyl-3-quinazolin)-4-one] formazans (6a-h). The structures of the synthesized compounds were determined by IR, 1HNMR, mass spectra and elemental analysis. The compounds synthesized were screened for antimicrobial and analgesic activity. Some of the synthesized compounds exhibited prominent antimicrobial and analgesic activities. 

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  • About the authors and Affiliations

    Author(s) Name:

    Rama Rao Nadendla, A. Narendra Babu*

    Affiliation(s) Name:

    Chalapathi Institute of Pharmaceutical Sciences, Guntur-522034

    *Corresponding author.
    A.Narendra Babu,Professor,
    Chalapathi Institute of Pharmaceutical Sciences,
    Chalapathi Nagar, Lam,
    Guntur-522034, Andhra Pradesh,INDIA

    Received on: 19-09-2010; Revised  on: 18-10-2010; Accepted on:13-12-2010

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    Rama Rao Nadendla, A. Narendra Babu*

    Title:Synthesis and Biological Evaluation of Some Novel Formazans
    Journal:Journal of Pharmacy Research
    Page No: (3-5)
  • Experimental Methods Keywords

    Methodology:Synthesis ,Antimicrobial, Analgesic activity
    Research Materials:Quinazolinone, formazans


Synthesis Quinazolinone formazans Antimicrobial Analgesic.

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