Journal: Journal of Pharmacy Research

Article Id: JPRS-P'Col-00001608
Title: Analgesic, Antioxidant Potential of Alcoholic (AL) Stem Bark Extract of Albizia lebbek (L.) Benth.
Category: Pharmacology
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  • Abstract

    Albizia lebbek (L.) Benth. is a medicinal plant. The plant is considered a most potent alexipharmic and every part of it is prescribed for the treatment of bites and stings from venomous animals.  AL stem bark extract of Albizia lebbek was screened to evaluate the analgesic and free-radical scavenging effect. The stem bark extract exhibited significant analgesic activity, reducing power and free radical scavenging effect on DPPH free radical, superoxide radical, and hydrogen peroxide. The analgesic activity of AL extract showed significant evaluation in pain threshold in comparison of control at dose of 250 mg/kg and 500mg/kg (p<0.01) at 90 min after extract administration. In addition to this, the antioxidant activities were concentration dependent which were compared with standard antioxidants such as BHA and ascorbic acid. The highest free radical scavenging of the stem bark extract was observed at concentration of 2500ìg/ml.

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    Author(s) Name:

    Ashwani1*, Prince P. Sharma1, Surender Singh2, Manjusha3, H.S. Lamba4

    Affiliation(s) Name:

    1Department of Pharmaceutical Science, Gurukul Kangri University, Hardwar-249404 Uttrakhand
    2All India Institute of Medical Sciences, New Delhi, India
    3Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra-136119 Haryana
    4 HR Institute of Pharmacy, Duhai, Ghaziabad

    *Corresponding author.
    Ashwani
    1Department of Pharmaceutical Science,
    Gurukul Kangri University, Hardwar-249404 Uttrakhand,India.

    Received on: 15-09-2010; Revised  on: 18-10-2010; Accepted on:13-12-2010

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    Author:

    Ashwani1*, Prince P. Sharma1, Surender Singh2, Manjusha3, H.S. Lamba4

    Title:Analgesic, Antioxidant Potential of Alcoholic (AL) Stem Bark Extract of Albizia lebbek (L.) Benth.
    Journal:Journal of Pharmacy Research
    Vol(issue):4 (January)
    Year:2011
    Page No: (15-18)
  • Experimental Methods Keywords

    Methodology:Antioxidant activity, Analgesic activity/ Nociceptive.
    Research Materials:Albizia lebbek

Keywords

Albizia lebbek Antioxidant activity Analgesic activity/ Nociceptive.

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