Journal: Journal of Pharmacy Research

Article Id: JPRS-PC-00001632
Title: Green nanoparticles synthesized from roots of Datura metel and evaluation of anti microbial activity
Category: Pharmaceutical Chemistry
  • Abstract
  • Audio Abstract
  • Authors
  • Pdf File
  • Citation
  • My Reference
  • Methodology
  • Abstract

    Metal Nanoparticles are explored in recent years as an alternative approach to effectively kill drug resistant pathogenic microorganisms. Silver nanoparticles (AgNPs) are the metal of choice for anti microbial agents. In this study, phytochemicals extracted from roots of Datura metel using n-hexane as solvent by Soxhlet extract technique. The extract were treated with silver nitrate and kept in the dark conditions for 48 hrs, for the appearance of colour change. The Plasmon peak was observed at 448nm. The physical appearance of these silver  nanoparticles was characterized using ultraviolet-visible spectroscopy, FT-IR, SEM, EDAX, TEM and X-ray diffraction techniques. Scanning electron microscopy (SEM) showed the clustered and irregular shapes of AgNPs, with a mean size of 50-85 nm. EDAX results confirmed the presence of silver nanoparticles in the adsorption peak of  2.30 keV. Nanoparticles average size determined by TEM studies and in identified in the range of  50-80nm. The antibacterial activity of the synthesized silver nanoparticles was tested against two micro-organisms using the disk diffusion method. The results reveal that silver nanoparticles synthesized using Datura metel root extract have potential antibacterial activity against Pseudomonas aeruginosa, Escherichia coli.

  • Abstract Audio

    Click Here

  • About the authors and Affiliations

    Author(s) Name:

    Meka Venkateswara Rao1, Medikondu Kishore2*, Y.Hanumantha Rao3

    Affiliation(s) Name:

    1Lecturer in Chemistry, PBN College, Nidubrolu, Andhra Pradesh, India
    2Department of Chemistry, SVRM College (Autonomous), Nagaram, India
    3Assoc.Prof. in Chemistry, Andhra Loyola College (Autonomous), Vijayawada, India

    *Corresponding author.
    Dr. Medikondu Kishore
    Department of Chemistry,
    SVRM College (Autonomous),
    Nagaram, India

    Received on:18-09-2016; Revised on: 16-10-2016; Accepted on: 20-11-2016

  • View Article File in pdf format.

    Article File
  • View Article Citation Here.

    0 View More
  • How to Cite my Article.

    Author:

    Meka Venkateswara Rao1, Medikondu Kishore2*, Y.Hanumantha Rao3

    Title:Green nanoparticles synthesized from roots of Datura metel and evaluation of anti microbial activity
    Journal:Journal of Pharmacy Research
    Vol(issue):10(11)
    Year:2016
    Page No: (730-734)
  • Experimental Methods Keywords

    Methodology: silver nanoparticles, Characterization, anti-microbial Activity.
    Research Materials:Roots of Datura metel

Keywords

Roots of Datura metel silver nanoparticles Characterization anti-microbial Activity.

Our Services

Most Downloaded List