Journal: Journal of Pharmacy Research

Article Id: JPRS-ND-00001639
Title: Phytochemical studies on Cichorium intybus L. (chicory) from Kashmir Himalaya using GC-MS
Category: Natural Drugs
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    Background:Cichorium intybus commonly called as chicory, coffee weed and blue sailor’s succory is traditionally used for the treatment of almost every disease particularly diseases related to heart, kidney and liver. Method: 0.2 g of the powdered seed, roots, stem and flower samples of Cichorium intybus from Kashmir Himalaya was equilibrated with 200 d/m of Cichorium intybus methanol for 24 h, separately. Supernatant was later reduced by heating to 2 d/m. The concentrated methanolic extracts were further subjected to GC-MS analysis.  Results: The GC-MS analysis determined the presence of 109 compounds from different parts of Cichorium intybus L. (chicory) in which 24 compounds were identified from seed, 22 compounds from root, 28 compounds from stem and 35 compounds from flower. The major metabolites from seed were 9,12-Octadecadienoic acid (Z,Z)- (35.03) and n-Hexadecanoic acid (34), from root were n-Hexadecanoic acid (24.37), 1,2-Benzenedicarboxylic acid, mono(2-ethylhexyl) ester (1.6), from stem were n-Hexadecanoic acid (35.14), 9,12-octadecadienoic acid (16.01) and from flower were 5-(hydroxymethyl)-2-furaldehyde (33.26), 9,12-Octadecadienoic acid (Z,Z)- (26.86) in terms of their percent area.  Conclusion: This study helps to predict the formula and structures of metabolites which can be further used in drug formulations and chicory from Kashmir Himalaya can be considered as potent candidate for pharmaceutical sector.

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    Author(s) Name:

    Bisma Malik1, Tanveer Bilal Pirzadah1, Inayatullah Tahir2, Malik Zainul Abdin3, Reiaz Ul Rehman1*

    Affiliation(s) Name:

    1Department of Bioresources, University of Kashmir, Srinagar, Jammu and Kashmir-190006, India
    2Department of Botany, University of Kashmir, Srinagar, Jammu and Kashmir-190006,India.
    3Department of Biotechnology, Jamia Hamdard, New Delhi-110062, India.

    *Corresponding author.
    Dr. Reiaz Ul Rehman
    Assistant Professor
    Department of Bioresources,
    University of Kashmir, Srinagar,
    Jammu and Kashmir-190006, India

    Received on:31-08-2016; Revised on: 27-09-2016; Accepted on: 23-11-2016

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    Author:

    Bisma Malik1, Tanveer Bilal Pirzadah1, Inayatullah Tahir2, Malik Zainul Abdin3, Reiaz Ul Rehman1*

    Title:Phytochemical studies on Cichorium intybus L. (chicory) from Kashmir Himalaya using GC-MS
    Journal:Journal of Pharmacy Research
    Vol(issue):10 (Nov)
    Year:2016
    Page No: (715-726)
  • Experimental Methods Keywords

    Methodology:GC-MS, ethenobotanical, phytochemical screening
    Research Materials:Cichorium intybus

Keywords

Cichorium intybus GC-MS ethenobotanical phytochemical

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