Journal: Drug Invention Today

Article Id: JPRS-CPS-00001779
Title: Synthesis, characterization and antimicrobial activity of metal complexes derived from nitro aniline and 3-aldehydosalicylic acid
Category: Chemistry and Parallel Synthesis
Section: Research Article
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     Objective: The aim of the present work was to synthesize different types of complex compounds of three Schiff base ligands with metal ions. Methods: New Schiff base ligands formed by the condensation of 3-Aldehydosalicylic acid with equimolar quantity of para, meta and ortho nitro aniline. The complexes of metal ions like Cu (II), Zn (II), Ni (II), Co (II)  with Schiff base ligands (ML2) have been synthesized at pH range7 . All the synthesized Schiff bases and metal complexes were characterized by elemental analysis, FTIR, 1HNMR and mass spectral data. Results: Study reveals that the Schiff base ligands involved the donor COOH, OH and Nitrogen atom. The ligands ML2 in metal complexes behave as dibasic tridentate OON at pH range7. Spectral analysis indicates square pyramidal geometries for all the complexes.  The Schiff bases and metal complexes were screened for their antifungal and antibacterial activities. Conclusion: The Cu (II) and Zn (II) complexes exhibited good antimicrobial activity when compared to the free ligand.

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    Author(s) Name:

    Shambulig Karabasannavar 1,2, Parvati Allolli 3, Basavaraj M. Kalshetty 4,*,

    Affiliation(s) Name:

    1, 2 Research and Development centre, Bharathiar University, Coimbatore and Department of Chemistry, BGMIT, Mudhol, District Bagalakoti, State Karnataka,India.

    3 Department of Pharmaceutical Chemistry, Karnataka State Women University, Bijapur, Karnataka ,India.

    4* Department of Chemistry, BLDE’S Science college, Jamkhandi, District Bagalakoti, State Karnataka, ,India.

    *Corresponding author.
    Dr. B.M.Kalshetty
    Department of chemistry, BLDE’s Science College,
    Jamkhandi.Bagalakoti Dist. Karnataka State, India

    Received on:19-01-2017; Revised on: 14-02-2017; Accepted on: 18-03-2017

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    Author:

    Shambulig Karabasannavar 1,2, Parvati Allolli 3, Basavaraj M. Kalshetty 4,*,

    Title:Synthesis, characterization and antimicrobial activity of metal complexes derived from nitro aniline and 3-aldehydosalicylic acid
    Journal:Drug Invention Today
    Vol(issue):9 (May)
    Year:2017
    Page No: (1-8)
  • Experimental Methods Keywords

    Methodology:Schiff base, Antimicrobial, dibasic.
    Research Materials:Nitro aniline

Keywords

Nitro aniline Schiff base Antimicrobial dibasic.

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