Journal: Journal of Pharmacy Research

Article Id: JPRS-PHDRS-00001809
Title: In vivo antianxiety and antidepressant activity of Hibiscus sabdariffa calyx extracts
Category: Pharmacognosy and Herbal Drugs related study
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    Objective: Different parts of H. sabdariffa have been used traditionally for treating several ailments including mental disorders. The present study was designed to evaluate the antianxiety and antidepressant potential of H. sabdariffa calyces using Elevated plus maze model and Forced swim test respectively. Material and Method: Petroleum ether (60-80 °C), chloroform, ethanol and aqueous extracts were evaluated for antianxiety and antidepressant activity. Results: Among all the extracts, ethanol extract showed significant antianxiety and antidepressant activity at a dose of 400 mg/kg. Phytochemical screening of the bioactive ethanol extract demonstrated the presence of flavonoids, terpenoids, tannins, anthocyanins, and glycosides.

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    Author(s) Name:

    Gulsheen Panesar, Ashwani Kumar*, Anupam Sharma

    Affiliation(s) Name:

    Department of Pharmacognosy, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh - 160 014, India

    *Corresponding author: Dr. Ashwani Kumar, University Institute of Pharmaceutical Sciences, Panjab University,Chandigarh - 160 014, India

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    Author:

    Gulsheen Panesar, Ashwani Kumar*, Anupam Sharma

    Title:In vivo antianxiety and antidepressant activity of Hibiscus sabdariffa calyx extracts
    Journal:Journal of Pharmacy Research
    Vol(issue):11(8)
    Year:2017
    Page No: (962-966)
  • Experimental Methods Keywords

    Methodology:antianxiety , antidepressant activity
    Research Materials:Hibiscus sabdariffa

Keywords

Calyces Elevated plus maze Flavonoids Forced swim Hibiscus sabdariffa

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