Journal: Drug Invention Today

Article Id: JPRS-PS-00001936
Title: The influence of sleep disorders on cognitive functions of a brain at patients with Type 2 diabetes
Category: Pharmacological Screening
Section: Research Article
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    Aim: The results of neuropsychological and sleep examination with the use of validated tests and questionnaires at 136 patients with the verified Type 2 diabetes mellitus diagnosis are presented in this article. The average age of the examined patients was 59.19± 5.649. The patients were in decompensated condition on indicators of carbohydrate metabolism. Materials and Methods: A totalof 136 patients older than 40 years with clinically and laboratory proved Type 2 diabetes were examined. The research included the participants of both genders living in Astana with a different national and ethnic origin to be convinced that the research advantage and burden are distributed evenly. Results and Discussion: By results of neuropsychological testing, cognitive functions of a brainwere reduced in all age groups at patients with Type 2 diabetes and were characterized by retardation of intellectual activity rate, the reduction of speech fluency, the depression of concentration of attention, memory disturbances of dynamic character. 77.9% of patients had sleep disorders, including, mild degree - 28% of patients; moderate - 30.9% of patients. Conclusion: The intrasomnic disorders including frequent night awakenings with the subsequent difficulty of sleep initiation prevailed. It is revealed that insomnia negatively influences on such cognitive functions of a brain as attention and visual-constructive skills.

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    Author(s) Name:

    A. S. Kasenova*, L. E. Eszhanova, D. D. Tursbekova, A. K. Durmanova

    Affiliation(s) Name:

    Department of Neurology, JSC “Medical University of Astana,” Astana City, Beibitshilik Street 49А, Kazakhstan.

    *Corresponding author: A. S. Kasenova, Department of Neurology, JSC “Medical University of Astana,” Astana City,Beibitshilik Street 49А, Kazakhstan

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    Author:

    A. S. Kasenova*, L. E. Eszhanova, D. D. Tursbekova, A. K. Durmanova

    Title:The influence of sleep disorders on cognitive functions of a brain at patients with Type 2 diabetes
    Journal:Drug Invention Today
    Vol(issue):9 (December)
    Year:2017
    Page No: (25-29)
  • Experimental Methods Keywords

    Methodology:Cognitive disturbances, Epworth sleepiness scale (ESS), Glycated hemoglobin HbA1c (%), Insomnia severity index, Insomnia, Montreal cognitive assessment test, Pittsburg sleep quality index
    Research Materials:Type 2 diabetes

Keywords

Cognitive disturbances Epworth sleepiness scale (ESS) Glycated hemoglobin HbA1c (%) Insomnia severity index Insomnia Montreal cognitive assessment test Pittsburg sleep quality index Type 2 diab

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