Journal: Journal of Pharmacy Research

Article Id: JPRS-CPRMS-00001942
Title: Personality traits of Russian men of 18–30 years old with different diplotypes in polymorphic loci COMT VAL158MET and MAOA-uVNTR
Category: Clinical Pharmacy and Related Medical Science
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    Aim and Scope: The article is devoted to the analysis of associations of genotype combinations of neurotransmitter system genes of MAOA and COMT with psychological features of young Russian men. Material and Methods:The study aimed finding associations of diplotypes by polymorphic loci Val158Met COMT and-uVNTR MAOA with such psychological characteristics as aggressiveness level and preferred forms of its expression, hostility level (Buss-Durkee Hostility Inventory), propensity to various kinds of addictive behavior, level of legitimized aggression, formally dynamic properties of individuality (diagnostication of personal inclination to deviant behavior), strategies of behavior in conflict, level of achievement motivation and personal traits (MMPI), were analyzed. Result and Discussion: It shows that carriers of a highly active diplotype have the lowest level of aggressiveness and are inclined to cooperate in the conflict; carriers of the highly active genotype MAOA in combination with the heterozygous genotype COMT have an average level of aggressiveness and high rates of emotional lability; carriers of low-level MAOA in combination with heterozygous genotype COMT have the highest rates of motivation to achieve success and verbal aggression; and carriers of low-level MAOA and highly active COMT are emotionally labile and non-aggressive. Men who are carriers of a low-active diplotype, have the highest level of aggressiveness and addiction to addictive behavior, which may indicate the association of this diplotype in a sample of young Russian men with social disadaptation. Conclusion: Russian men, carriers of different diplotypes at polymorphic loci Val158Met of gene COMT and -uVNTR of gene MAOA, have significant differences in the severity of such psychological characteristics as the level and forms of aggression and hostility, propensity to deviant behavior, strategies of behavior in a conflict, the level of motivation to achieve success, the formal dynamic properties of individuality, and the level of emotional lability, depressiveness, and suspicion

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    Author(s) Name:

    Pavel N Ermakov1, Elena V Vorobyeva2*, Ekaterina M Kovsh1, Irina V Abakumova3, Olga D Fedotova4, Marina P Aralova1, Wladimir W Latun5, Lubov Ya. Horonko6

    Affiliation(s) Name:

    1Department of Psychophysiology and Clinical Psychology, Academy of Psychology and Educational Sciences, Southern Federal University, 13 Mikhaila Nagibinard., Rostov-on-Don, 344038, Russia,
    2Department of Psychophysiology and Clinical Psychology, Faculty of Psychology, Pedagogy and Defectology, Don State Technical University, 1 Gagarin sq., Rostov on Don, 344000, Russia,
    3Department of General and Counselling Psychology, Faculty of Psychology, Pedagogy and Defectology, Don State Technical University, 1 Gagarin sq., Rostov on Don, 344000, Russia,
    4Department of Primary Education, Faculty of Psychology, Pedagogy and Defectology, Don State Technical University, 1 Gagarin sq., Rostov-on-Don, 344000, Russia;
    5Department of social-economic geography and nature management,Institute for Earth Sciences,Southern Federal University, 105/42 BolshayaSadovayastr., Rostov-on-Don, 344006, Russia,
    6Department education and pedagogical Sciences, Academy of Psychology and Pedagogy, Southern Federal University, 105/42 BolshayaSadovayastr., Rostov-on-Don, 344006, Russia

    *Corresponding author: Elena V Vorobyeva Department of Psychophysiology and Clinical Psychology, Faculty of Psychology, Pedagogy and defectology, Don State Technical University, 1 Gagarin sq., Rostov on Don, 344000, Russia

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    Author:

    Pavel N Ermakov1, Elena V Vorobyeva2*, Ekaterina M Kovsh1, Irina V Abakumova3, Olga D Fedotova4, Marina P Aralova1, Wladimir W Latun5, Lubov Ya. Horonko6

    Title:Personality traits of Russian men of 18–30 years old with different diplotypes in polymorphic loci COMT VAL158MET and MAOA-uVNTR
    Journal:Journal of Pharmacy Research
    Vol(issue):11(12)
    Year:2017
    Page No: (1559-1564)
  • Experimental Methods Keywords

    Methodology:Diplotypes, Genotype, Neurotransmitter system genes, Polymorphic loci, uVNTR MAOA, Val158Met COMT,
    Research Materials:ussian men of 18–30 years old

Keywords

Diplotypes Genotype Neurotransmitter system genes Polymorphic loci uVNTR MAOA Val158Met COMT Young men

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