Journal: Drug Invention Today

Article Id: JPRS-Other-00002018
Title: Vitamin D is a suggested target in hypertensive Iraqi patients management
Category: Others ( DIT Related Science )
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    Aim: Hypertension (HTN) is the leading attributable risk for cardiovascular disease. In the Middle East, the disease continues to be a worrying public health issue with modest blood pressure control rates. Vitamin D possesses antihypertensive acts through its negative regulation of renin-angiotensin aldosterone system, antioxidant, and anti-angiogenic effects. Materials and Method: In this cross-sectional study, a total of 68 Vitamin D naive HTN Iraqi patients with a mean age (54.8 ± 13.2) were investigated in comparison to matched 31 normotensive apparently healthy individuals. Serum Vitamin D level estimation was done in both groups by immunofluorescence assay, and the dependency sufficiency (normal) values were those ≥30 ng/ml. Result and Discussion: Vitamin D sufficiency was less prevalent among the patients group versus controls (4.41% vs. 54.83%). The mean of Vitamin D serum levels among patients “unexpectedly” was 13.13 ± 8.86 ng/ml which were significantly (P = 0.000) lower than that of controls 36.44 ± 16.66 ng/ml. We also observed a significant (P = 0.007) inverse correlation between Vitamin D levels and the obesity index; waist to height ratio in HTN patients. Conclusion: It can be concluded that a deficient level of Vitamin D is highly prevalent in Iraqi HTN patients, and low levels tend to correlate with obesity.

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    Author(s) Name:

    Rawia M. Yousif, Majid M. Mahmood*

    Affiliation(s) Name:

    Department of Biology, College of Science, Al-Mustansiriya University, Baghdad, Iraq

    *Corresponding author: Majid M. Mahmood, Department of Biology, College of Science, Al-Mustansiriya University, Baghdad, Iraq

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    Author:

    Rawia M. Yousif, Majid M. Mahmood*

    Title:Vitamin D is a suggested target in hypertensive Iraqi patients management
    Journal:Drug Invention Today
    Vol(issue):9(3)
    Year:2017
    Page No: (102-105)
  • Experimental Methods Keywords

    Methodology: cross-sectional study, immunofluorescence assay
    Research Materials:Vitamin D

Keywords

Hypertension Obesity Vitamin D Waist-to-height ratio

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