Journal: Journal of Pharmacy Research
Title: In vitro anti-inflammatory activity of Garcinia hanburyi extract
Category: Pharmacology
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Abstract
Aim: Garcinia hanburyi belongs to the family Clusiaceae. In the present study, G. hanburyi has been selected to test for the anti-inflammatory activity by proteinase inhibitory activity, membrane stabilization, and albumin denaturation assay at various concentrations. Materials and Methods: The whole plant was dried, extracted to obtain Xanthone rich extract. Phytochemical studies of extract showed the presence of phenols, alkaloids, steroids, resins, and saponins. The natural sources such as plants are an abundant source having various medicinal properties. Results and Discussion: The results showed that the extract from G. hanburyi at a concentration from 100 to 500 µg/ml protects protein denaturation. Significant proteinase inhibitory activity was seen at the concentration of 400 µg/ml and 500 µg/ml. Heat-induced hemolysis of erythrocyte was considerably inhibited at the concentrations of 400 µg/ml. Conclusion: The results which are obtained from the present study shows that the extract of G. hanburyi can be a promising resource of anti-inflammatory agents.
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About the authors and Affiliations
Author(s) Name: J. Narayanan*, V. Chitra
Affiliation(s) Name: Department of Pharmacology, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, India
*Corresponding author: J. Narayanan, Department of Pharmacology, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, India.
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Author: J. Narayanan*, V. Chitra
Title: In vitro anti-inflammatory activity of Garcinia hanburyi extract Journal: Journal of Pharmacy Research Vol(issue): 12 (April) Year: 2018 Page No: (571-576) -
Experimental Methods Keywords
Methodology: Anti-Inflammatory, Human red blood cell, Membrane stabilization Research Materials: Garcinia hanburyi
Keywords
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