Journal: Drug Invention Today

Article Id: JPRS-D(DD)-00002071
Title: A brief review on current antifungal agents
Category: Drug (Discovery/Development)
Section: Review Article
  • Abstract
  • Audio Abstract
  • Authors
  • Pdf File
  • Citation
  • My Reference
  • Methodology
  • Abstract

    Nowadays, most of fungal infections such as candidoses can range from superficial mucous membrane infection to life- threatening systemic mycoses. Candida infections give significant clinical problem globally due to most rapid rise in compromised host populations including HIV/AIDS, organ transplant recipients, and patients those are on chemotherapy. In addition to this, a sharp increase in the aging populations which are susceptible to fungal infections is expected in next few decades. Antifungal drugs for these problems are relatively difficult to develop compared to the antibacterial drugs owing to the eukaryotic nature of the cells. Therefore, only a handful of antifungal agents are currently available to treat the myriad of fungal infections. Moreover, the rising antifungal resistance and host-related adverse reactions have limited the antifungal arsenal against fungal pathogens. In this review topic, we tried to update the theoretical aspects pertaining to the antifungal drug discovery, i.e., proposed novel mechanisms, new drug targets, and pathways. Here, we are reporting some new antifungal molecules.

  • Abstract Audio

    No Audio file found

  • About the authors and Affiliations

    Author(s) Name:

    Anbhule Sachin J1 , M. Vijey Aanandhi 2 *

    Affiliation(s) Name:

    1 Research Scholar, Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, VISTAS, Pallavaram, Chennai-600117, Tamil Nadu, India,

    2 Professor and Head, Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, VISTAS, Pallavaram, Chennai-600117, Tamil Nadu, India

    *Corresponding author: Dr. M. Vijey Aanandhi, Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai – 600 117, Tamil Nadu, India.

  • View Article File in pdf format.

    Article File
  • View Article Citation Here.

    0 View More
  • How to Cite my Article.

    Author:

    Anbhule Sachin J1 , M. Vijey Aanandhi 2 *

    Title:A brief review on current antifungal agents
    Journal:Drug Invention Today
    Vol(issue):10 (Jan)
    Year:2018
    Page No: (76-79)
  • Experimental Methods Keywords

    Methodology: Fungal infection, In-vitro, Eukaryotic, Life threatening
    Research Materials:Antifungal agents

Keywords

Antifungal Fungal infection In-vitro Eukaryotic Life threatening

Our Services

Most Downloaded List