Journal: Drug Invention Today

Article Id: JPRS-BMa-00002075
Title: Chromatographic fingerprinting analysis of secondary metabolites present in ethanolic extract of Acokanthera schimperi leaves by high-performance thin-layer chromatography technique
Category: Biological Macromolecules
Section: Research Article
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    Objective: Acokanthera schimperi belonging to the family Apocynaceae is well known in Ethiopia to treat skin infections and malaria, organic extracts of this plant exhibit antioxidant, anti-inflammatory, antimicrobial activity properties, and it has a long history of being used as an herbal remedy. Therefore, the main objective of the present study was to investigate the chemical fingerprint profile of glycosides, steroids, phenols, and tannins of ethanolic extract of A. schimperi using high- performance thin-layer chromatography (HPTLC) technique. Methods: HPTLC profile of glycosides, steroids, phenols, and tannins of ethanolic extract of A. schimperi were done and profiles were developed using CAMAG LINOMAT- 5 instrument. Results: From the results, it is conformed that the ethanolic extract of A. schimperi showed the presence of secondary metabolites such as glycosides, steroids, phenols, and tannins. Conclusion: Based on the results, it can be concluded that the ethanolic extract of A. schimperi is the potential sources for pharmacology for devolvement of plant-derived bioactive novel drugs for curing various diseases.

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    Author(s) Name:

    K. Krishna Chaithanya1 , Zenebe Hagos1 , D. Malarvizhi 2 , K.Poornima2 , V. K. Gopalakrishnan1 *

    Affiliation(s) Name:

    1 Department of Chemistry, College of Natural and Computational Sciences, Aksum University, Axum, Ethiopia,

    2 Department of Biochemistry, Karpagam Academy of Higher Education, Coimbatore, India

    *Corresponding author: Dr. V. K. Gopalakrishnan, Department of Chemistry, College of Natural and Computational Sciences, Aksum University, Post Box. No 1010, Axum, Tigray Region, Ethiopia.

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    Author:

    K. Krishna Chaithanya1 , Zenebe Hagos1 , D. Malarvizhi 2 , K.Poornima2 , V. K. Gopalakrishnan1 *

    Title:Chromatographic fingerprinting analysis of secondary metabolites present in ethanolic extract of Acokanthera schimperi leaves by high-performance thin-layer chromatography technique
    Journal:Drug Invention Today
    Vol(issue):10 (Jan)
    Year:2018
    Page No: (95-101)
  • Experimental Methods Keywords

    Methodology: Fingerprinting, High-performance thin-layer chromatography plant-derived secondary metabolites
    Research Materials:Acokanthera schimperi

Keywords

Acokanthera schimperi Fingerprinting High-performance thin-layer chromatography plant-derived secondary metabolites

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