Journal: Drug Invention Today

Article Id: JPRS-pp-00002105
Title: Role of zinc supplements in pediatric acute and persistent diarrhea: A prospective observational study in a tertiary care hospital
Category: Pharmacy Practice
Section: Research Article
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    Aim and Objectives: The aim of the study was to assess the therapeutic effect of zinc supplements in patients with acute and persistent diarrhea. To monitor the effect of supplemental zinc given along with oral rehydration therapy during acute and persistent diarrhea. To assess the number of episodes of diarrhea in acute and persistent diarrhea. Materials and Methods: A prospective observational study was carried for a time period of 6 months from November 2015 to April 2016 in a tertiary care hospital. Data were collected from the pediatric subjects diagnosed with acute and persistent diarrhea using self-designed patient pro forma. The study was approved by the Institutional Ethics Committee ref - IEC/ DOPI/2016/21. Results: In this study, 100 patients with diarrhea were selected. Out of 100 patients, 83 were selected based on inclusion and exclusion criteria. Among the study population of 83, 22 patients (27%) were in the age group of 6–12 months, 18 patients (21%) were in the age group of 1–2 years, 17 patients (20%) were in the age group of 2–3 years, 14 patients (16%) were in the age group of 3–4 years, and 12 patients (14%) were in the age group of 4–5 years. It indicates that majority of people in age group of infants were most affected with diarrhea. In this prospective study comprising 83 diarrhea patients treated with zinc supplements, in that 38 (46%) were male child and 45 (54%) were female child, which confirms that female child was more likely to be affected with diarrhea than male subjects. Conclusion: From the current study, it was concluded that with zinc supplementation on acute and persistent diarrhea was more effective than oral rehydration salts. Zinc supplements reduced the duration, severity, and number of diarrheal episodes. Zinc supplements are given 20 mg per day for 14 days. It was extremely effective in patients with diarrhea.

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    Author(s) Name:

    Muddala Vara Prasanna Rao*, Vaddi Mounika, Oliver Joel Gona, Dega Sunil Kumar, P. Shanmugasundaram

    Affiliation(s) Name:

    Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai - 600 117, Tamil Nadu, India

    *Corresponding author: Dr M.VaraPrasanna Rao, Assistant Professor, Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Velan Nagar, P.V. Vaithiyalingam Road, Pallavaram,Chennai - 600 117, Tamil Nadu, India.

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    Author:

    Muddala Vara Prasanna Rao*, Vaddi Mounika, Oliver Joel Gona, Dega Sunil Kumar, P. Shanmugasundaram

    Title:Role of zinc supplements in pediatric acute and persistent diarrhea: A prospective observational study in a tertiary care hospital
    Journal:Drug Invention Today
    Vol(issue):10 (Feb)
    Year:2018
    Page No: (189-191)
  • Experimental Methods Keywords

    Methodology:Acute diarrhea, Diarrhea, Persistent diarrhea
    Research Materials:Zinc supplements

Keywords

: Acute diarrhea Diarrhea Persistent diarrhea Zinc supplements

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