Journal: Drug Invention Today

Article Id: JPRS-pp-00002118
Title: A prospective study of drug utilization pattern of cardiac inotropes in cardiac intensive care unit at a tertiary care hospital
Category: Pharmacy Practice
Section: Research Article
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    Background and Objective: Inotropes have been fundamental for the resuscitation of acute cardiogenic shock for decades. There are two types of inotropes: Positive inotrope and negative inotrope. Positive inotrope increases the force of contraction of the heart, and negative inotrope weakens the heart beats. There is a marked difference in the usage pattern of inotrope in the treatment of hospitalized patients for various cardiovascular diseases. The main of the study was to analyze the prescribing patterns of cardiac inotropes in the cardiac intensive care unit (CTICU). Materials and Methods: The prospective observational study was carried out for the duration of 6 months in the department of CTICU at a tertiary hospital, Chennai. A total of 91 patients were selected for the study. Patient case sheets (including patient demographic details, drug therapy, and laboratory investigations) were used to extract the necessary data. The percentage of data was calculated with the help of Microsoft Excel sheet, and the sample size was calculated using the formula. Results: Of the 91 patients enrolled in the study, majority were male (67) and were found in the age group of 51–60 years. Adrenaline 50 (54.95%) was most commonly prescribed positive inotrope, followed by noradrenaline 37 (40.66%) and dobutamine 35 (38.46%). Amiodarone 18 (19.78%) was most commonly prescribed negative inotropes, followed by propranolol 5 (5.59%) and nicorandil 3 (3.30%). The mean duration of stay in the hospital was 7.42 days. The average number of inotropes prescribed per prescription was 1.71. The average number of drugs prescribed per prescription was 13.34. Conclusion: Positive inotropes were the most frequently prescribed drug. Mean number of drugs per prescription were high. The prescribing pattern could be improved by reducing number of drugs in prescription and varies in between positive and negative inotropes to a greater extent.

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    Author(s) Name:

    S. Lavanya*, G. Oliver Joel, S. Aswathy, A. Anju, M. M. Jintu, M. S. Sandra, D. Krishna kumar

    Affiliation(s) Name:

    1 Department of Pharmacy Practice, C.L. Baid Metha College of Pharmacy, Chennai, Tamil Nadu, India

    *Corresponding author: Mrs. S. Lavanya, Department of Pharmacy Practice, C. L. Baid Metha College of Pharmacy, Jyothi Nagar, Rajiv Gandhi Salai, Thorapakkam, Chennai, Tamil Nadu, India.

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    Author:

    S. Lavanya*, G. Oliver Joel, S. Aswathy, A. Anju, M. M. Jintu, M. S. Sandra, D. Krishna kumar

    Title:A prospective study of drug utilization pattern of cardiac inotropes in cardiac intensive care unit at a tertiary care hospital
    Journal:Drug Invention Today
    Vol(issue):10 (Feb)
    Year:2018
    Page No: (244-247)
  • Experimental Methods Keywords

    Methodology:Drug utilization, Inotropes, Medications
    Research Materials:Various cardiovascular diseases

Keywords

Drug utilization Inotropes Medications

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