Journal: Journal of Pharmacy Research

Article Id: JPRS-PB-00002148
Title: Exploring the function in the hypothetical junction of Yersinia enterocolitica subsp. palearctica Y11 - A bioinformatics approach
Category: Pharmaceutical Biotechnology
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    Aim: Yersinia enterocolitica subsp. palearctica Y11 is a bacterium known for spreading human gastroenteritis and in relation study investigated functional features in the hypothetical proteins encoded by Y. enterocolitica subsp. palearctica Y11 by conserved domain search and protein structure prediction. Materials and Methods: Five conserved domain analysis web tools used to perform the search as conserved domain database BLAST, INTERPROSCAN, Pfam, Uniprot, and CATH along with PS2 protein structure prediction server for structure modeling. Results and Conclusion: These web tools successfully predicted the function in 13 hypothetical proteins. Overall, results of Y. enterocolitica subsp. palearctica Y11 hypothetical proteins were documented for coding enzymes and other functions. Further, investigation is suggested to understand the role of these hypothetical proteins in metabolic pathway which will be useful for organism bio-controlling.

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    Author(s) Name:

    Mayur Dange1 , Archana Umate1 , Dilip Gore2 *, Maithili Hedaoo1 , Shreya Fadnavis1 , M A Soni 1 , Anup D Chahande1

    Affiliation(s) Name:

    1 Department of Biotechnology, Priyadarshini Institute of Engineering and Technology, Mouza Shivangaon, Behind CRPF Campus, Hingna Road, Nagpur – 440 019, Maharashtra, India,

    2 Sai Biosystems Private Limited, Plot No. 271 Raghuji Nagar, Nagpur – 440 009, Maharashtra, India

    *Corresponding Author: Dilip Gore, Sai Biosystems Private Limited, Plot No. 271 Raghuji Nagar, Nagpur – 440 019, Maharashtra, India.

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    Author:

    Mayur Dange1 , Archana Umate1 , Dilip Gore2 *, Maithili Hedaoo1 , Shreya Fadnavis1 , M A Soni 1 , Anup D Chahande1

    Title:Exploring the function in the hypothetical junction of Yersinia enterocolitica subsp. palearctica Y11 - A bioinformatics approach
    Journal:Journal of Pharmacy Research
    Vol(issue):12(5)
    Year:2018
    Page No: (673-678)
  • Experimental Methods Keywords

    Methodology:Hypothetical proteins, bioinformatics, conserved domains, protein function
    Research Materials:Yersinia enterocolitica subsp. palearctica Y11

Keywords

Hypothetical proteins bioinformatics conserved domains protein function

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