Journal: Drug Invention Today

Article Id: JPRS-PS-00002188
Title: Anticancer and antibacterial potential of green silver nanoparticles synthesized from Maytenus senegalensis (L.) leaf extract and their characterization
Category: Pharmacological Screening
Section: Research Article
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    Background: Metal nanoparticles are explored in recent years as an alternative approach to effectively kill drug-resistant pathogenic microorganisms. The present research study enumerates the synthesis and characterization of silver nanoparticles (AgNPs) from the n-hexane leaf extract of Maytenus senegalensis (L.). Methods: The synthesized AgNPs were initially noticed through visual color and also monitored using ultraviolet-visible absorption spectroscopy, and the surface plasmon resonance of AgNPs at 439 nm was observed. The synthesized nanoparticles further characterized by Fourier-transform infrared spectroscopy for functional group identification, morphology, and sizes of NPs were identified by scanning electron microscope and transmission electron microscope; SAED and X-ray diffraction patterns confirmed the presence of highly crystalline and face-centered cubic structure AgNPs and elemental composition by energy dispersive X-ray spectroscopy analysis. Results: The biosynthesized AgNPs exhibited a strong antimicrobial activity against Gram-positive and Gram- negative bacteria, with minimum bactericidal concentrations. Conclusion: It could be concluded that AgNPs based on M. senegalensis leaf extract can be used efficiently in the production of potential anticancer and antimicrobial for commercial application.

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    Author(s) Name:

    Medikondu Kishore1 *, Abeer Talib Abdulqader2 , Hanan Shihab Ahmad2 , Y. Hanumantharao3

    Affiliation(s) Name:

    1 Department of Chemistry, SVRM College (A), Nagaram, Andhra Pradesh, India,

    2 Department of Pathological Analysis, Al Door Technical Institute, Northern Technical University, Iraq,

    3 Department of Chemistry, Andhra Loyola College (A), Vijayawada, Andhra Pradesh, India.

    *Corresponding author: Medikondu Kishore, Department of Chemistry, SVRM College (A), Nagaram, Andhra Pradesh, India.

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    Author:

    Medikondu Kishore1 *, Abeer Talib Abdulqader2 , Hanan Shihab Ahmad2 , Y. Hanumantharao3

    Title:Anticancer and antibacterial potential of green silver nanoparticles synthesized from Maytenus senegalensis (L.) leaf extract and their characterization
    Journal:Drug Invention Today
    Vol(issue):10 (April)
    Year:2018
    Page No: (554-561)
  • Experimental Methods Keywords

    Methodology:Anticancer activity, Antimicrobial, Characterization, Green Synthesis, Silver Nanoparticles
    Research Materials: Maytenus senegalensis (L.) ,nanoparticles

Keywords

Anticancer activity Antimicrobial Characterization Green Synthesis Maytenus senegalensis leaf extract Silver Nanoparticles

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