Journal: Journal of Pharmacy Research

Article Id: JPRS-PCS-00002200
Title: Pulsatile drug delivery system - A review article
Category: Pharmaceutics
Section: Review Article
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    Pulsatile drug delivery systems (PDDS) are developed to deliver drug according to circadian behavior of diseases. They deliver the drug at the right time, action and in the right amount, which provides more benefit than conventional dosages and increased patient compliance. The drug is released rapidly and completely as a pulse after a lag time. These systems are beneficial for drugs with chrono-pharmacological behavior, where nighttime dosing is required and for the drugs having a high first-pass effect and having specific site of absorption in the gastrointestinal tract. This article covers methods and marketed technologies that have been developed to achieve pulsatile delivery. Diseases wherein PDDS are promising include asthma, peptic ulcers, cardiovascular, arthritis and attention deficit syndrome in children and hypercholesterolemia.

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    Author(s) Name:

    Roaa A. Nief*, Halah Talal Sulaiman, Saba Abdulhadi Jabir

    Affiliation(s) Name:

    Department of Pharmaceutics, College of Pharmacy, University of Baghdad, Baghdad, Iraq.

    *Corresponding author: Roaa A. Nief, Department of Pharmaceutics, College of Pharmacy, University of Baghdad, Baghdad, Iraq.

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    Author:

    Roaa A. Nief*, Halah Talal Sulaiman, Saba Abdulhadi Jabir

    Title:Pulsatile drug delivery system - A review article
    Journal:Journal of Pharmacy Research
    Vol(issue):12 (May)
    Year:2018
    Page No: (764-770)
  • Experimental Methods Keywords

    Methodology:Pulsatile drug delivery system, Capsular system, Rupturable coating
    Research Materials: Drug

Keywords

Pulsatile drug delivery system Capsular system Rupturable coating

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