Journal: Journal of Pharmacy Research

Article Id: JPRS-ND-00002266
Title: Phytochemical and in vitro antioxidant activities of methanol leave extract of Alternanthera basiliana.
Category: Natural Drugs
Section: Research Article
  • Abstract
  • Audio Abstract
  • Authors
  • Pdf File
  • Citation
  • My Reference
  • Methodology
  • Abstract

    Background and Aim: Plant-derived antioxidants can play a role in the prevention of oxidative stress-related diseases. Alternanthera brasiliana has been reported to have many pharmacological properties and thus the need to evaluate its antioxidant and possible mode of actions. The study evaluated the antioxidant properties of methanol extract prepared from A. brasiliana leaves in vitro. Methods: This was done using various in vitro antioxidant assay protocols which includes diphenyl-picrylhydrazyl free radical scavenging, metal chelating, reducing ability, hydroxyl radical, and ferric reducing antioxidant properties assay. The different antioxidant potentials were compared with suitable standard antioxidants such as ascorbic acid, quercetin, Trolox, and ethylenediaminetetraacetic acid. Phytochemical screening of the extract was done qualitatively. Results: The phytochemical results showed the presence of flavonoids, saponin, steroids, and tannin. While the extract elicited a concentration-dependent inhibition (%), its antioxidant activities were significantly less than the standard antioxidants (P < 0.05). Conclusion: The results obtained in this study provide evidence that A.brasiliana scavenges free radicals and can serve as a good source of natural antioxidant and justifies its potential use in the management or prevention of oxidative stress-related diseases.

  • Abstract Audio

    No Audio file found

  • About the authors and Affiliations

    Author(s) Name:

    Ugwu Chidiebere Emmanuel 1* , Suru Stephen Monday1 , Dike Charles Chijioke1 , OkpogbaAloysius Ngozi 1 , Egba Simeon2

    Affiliation(s) Name:

    1 Department of Human Biochemistry, Faculty of Basic Medical Sciences, College of Health Sciences, Nnamdi Azikiwe University, Nnewi Campus, Nigeria,

    2 Department of Biochemistry, College of Natural and Applied Sciences, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria

    *Corresponding author: Ugwu Chidiebere Emmanuel, Department of Human Biochemistry, Faculty of Basic Medical Sciences, College of Health Sciences, NnamdiAzikiwe University, Nnewi Campus, Nigeria.

  • View Article File in pdf format.

    Article File
  • View Article Citation Here.

    0 View More
  • How to Cite my Article.

    Author:

    Ugwu Chidiebere Emmanuel 1* , Suru Stephen Monday1 , Dike Charles Chijioke1 , OkpogbaAloysius Ngozi 1 , Egba Simeon2

    Title:Phytochemical and in vitro antioxidant activities of methanol leave extract of Alternanthera basiliana.
    Journal:Journal of Pharmacy Research
    Vol(issue):12 (June)
    Year:2018
    Page No: (835-839)
  • Experimental Methods Keywords

    Methodology:Antioxidant, In vitro, Phytochemical analysis
    Research Materials: Alternanthera brasiliana

Keywords

Alternanthera brasiliana Antioxidant In vitro Phytochemical

Our Services

Most Downloaded List