Journal: Drug Invention Today

Article Id: JPRS-PS-00002326
Title: Plant Extracts with Activity against Oral Bacteria
Category: Pharmacological Screening
Section: Research Article
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    The association between oral diseases and oral microbiota is well established. The development of dental caries involves Gram-positive bacteria (mutans streptococci, lactobacilli, and actinomycetes). Periodontal diseases have been linked to anaerobic Gram-negative bacteria (Porphyromonas gingivalis, Actinobacillus, Prevotella, and Fusobacterium). Given the incidence of oral disease, increased resistance by bacteria to antibiotics, adverse affects of some antibacterial agents currently used in dentistry there is a need for alternative prevention and treatment options that are safe, effective, and economical. While several agents are commercially available, these chemicals can alter oral microbiota and have undesirable side-effects. In this review, plant extracts or phytochemicals that inhibit the growth of oral pathogens, reduce the development of biofilms and dental plaque, influence the adhesion of bacteria to surfaces, and reduce the symptoms of oral diseases will be discussed.

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    Author(s) Name:

    Jacob Mathew Philip1*, K. Mahalakshmi2, L. Jeyanthi Rebecca3, C. J. Venkatakrishnan4, Chitra R. Chandran5

    Affiliation(s) Name:

    1Research Scholar, Sree Balaji Dental College, BIHER, Bharath University, Velachery Main Rd, VGP Rajesh Nagar, Pallikaranai, Chennai, Tamil Nadu 600100.

    2Dept. of Microbiology, Sree Balaji Dental College, BIHER, Bharath University, Velachery Main Rd, VGP Rajesh Nagar, Pallikaranai, Chennai, Tamil Nadu 600100.

    3Dept. of Biotechnology, BIHER, Bharath University, 173, New Agaram Rad, Selaiyur, Chennai, Tamil Nadu 600073,India.

    4Dept of Prosthodontics, Tagore Dental College, Near Vandalur, Melakkottaiyur Post, Rathinamangalam, Tamil Nadu 600127, India.

    5Dept. of Periodontics, Tagore Dental College, Near Vandalur, Melakkottaiyur Post, Rathinamangalam, Tamil Nadu 600127, India

    *Corresponding author: Dr. Jacob Mathew Philip, BIHER, Bharath University, 173, New Agaram Road, Selaiyur, Chennai - 600 073, Tamil Nadu, India.

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    Author:

    Jacob Mathew Philip1*, K. Mahalakshmi2, L. Jeyanthi Rebecca3, C. J. Venkatakrishnan4, Chitra R. Chandran5

    Title:Plant Extracts with Activity against Oral Bacteria
    Journal:Drug Invention Today
    Vol(issue):10 (July)
    Year:2018
    Page No: (1088-1090)
  • Experimental Methods Keywords

    Methodology:Antibacterial, Oral bacteria, Oral disease
    Research Materials:Plant extracts

Keywords

Antibacterial Oral bacteria Oral disease Plant extracts

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