Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002347
Title: Evaluation of salivary total proteins, albumin, globulin, and A/G ratio among healthy individuals and patients with chronic periodontitis
Category: Pharmacology
Section: Research Article
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    Aim: The aim of this study is to estimate the level of salivary total proteins, albumin, globulin, and A/G ratio among healthy individuals and patients with chronic periodontitis. Materials and Methods: The saliva samples were collected from a total of 20 individuals where 10 samples from normal individuals as a control group and 10 samples from chronic periodontitis patients. Salivary protein estimation was done based on the biuret method. Salivary albumin was estimated using the bromocresol green method. Results: The results of our study showed higher levels of total protein, albumin, and globulin in chronic periodontitis patients as compared to healthy individuals. The increased protein levels can be due to the inflammatory process that activates the sympathetic system to enhance the synthesis and secretion of some proteins, thereby increasing the protective potential of saliva against the diseases. Conclusion: Useful diagnostic information can be obtained by determining the total proteins, albumin, globulin, and A/G ratio. Significant changes in these values can pinpoint specific changes. As saliva is one of the major constituents of the oral cavity, estimation of total salivary proteins helps in the diagnosis of chronic periodontitis, thus facilitating early prognosis and treatment.

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    Author(s) Name:

    T. Priadarsini 1 , R. Gayathri 2 *, V. Vishnu Priya2

    Affiliation(s) Name:

    1 Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: R. Gayathri, Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, 160, Poonamallee High Road, Chennai – 600 077, Tamil Nadu, India.

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    Author:

    T. Priadarsini 1 , R. Gayathri 2 *, V. Vishnu Priya2

    Title:Evaluation of salivary total proteins, albumin, globulin, and A/G ratio among healthy individuals and patients with chronic periodontitis
    Journal:Drug Invention Today
    Vol(issue):10 (July)
    Year:2018
    Page No: (1175-1178)
  • Experimental Methods Keywords

    Methodology:Biuret method
    Research Materials:healthy individuals and patients

Keywords

A/G ratio Albumin Globulin Periodontitis Total protein

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