Journal: JPR:BioMedRx:An International Journal

Article Id: JPRS-PDRS-0000238
Title: Evaluation of in vitro antioxidant activity of plant Chrozophora plicata
Category: Plant Drugs Related Study
Section: Research Article
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    Free radical induced oxidative stress is involved in the pathogenesis of various diseases and disorders. Antioxidants are the free radical scavengers which protect human body against the oxidative stress. The present study was carried out to evaluate the in vitro antioxidant properties of 70% ethanol extract of Chrozophora plicata plant (Leaves) by estimation of reducing power and scavenging activity of Superoxide anion, Hydroxyl radical and Nitric oxide anion. The Ethanolic extract of leaves had shown concentration dependent reducing power. This exhibited higher reducing power at 100mg concentration of extract as similar to standard drug (sodium metabisulphite 25mg). Similarly, Ethanolic extract of Chrozophora plicata also have shown concentration dependant superoxide scavenging activity, hydroxyl radical scavenging activity and Nitric oxide radical scavenging activities at 100mg but to a lesser extent than standard drug (sodium metabisulphite 25mg). From the preliminary studies, it was found that the leaves of Chrozophora plicata plant contain triterpenoids and related compounds (sterols, alcohols and hydrocarbons), phenolic compounds (flavonoids, lignans, coumarins, tannins, phenanthrenes, quinones, phenolic acids, etc.) that are possessing antioxidant properties.

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    Author(s) Name:

    K.Sunil kumar1*, A.Srinivasa Rao2, K.Satyanarayana3

    Affiliation(s) Name:

    1Vijaya College of Pharmacy,Munaganoor – 501511, Hyderabad, A.P, India
    2 Bhaskar Pharmacy college,Yenkapally, moinabad, R.R Dist, A.P,Hyderabad- 500075
    3Vimta Labs Ltd., IDA Cherlapally, Hyderabad 500051, AP, India

    *Corresponding author.
    K.Sunil kumar
    Vijaya College of Pharmacy,
    Munaganoor,Hyderabad-501511, AP, India


    Received on:17-09-2012; Revised on: 19-10-2012; Accepted on:10-12-2012

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    Author:

    K.Sunil kumar1*, A.Srinivasa Rao2, K.Satyanarayana3

    Title:Evaluation of in vitro antioxidant activity of plant Chrozophora plicata
    Journal:JPR:BioMedRx:An International Journal
    Vol(issue):1 (January )
    Year:2013
    Page No: (47-50)
  • Experimental Methods Keywords

    Methodology:Antioxidant activity
    Research Materials:Chrozophora plicata

Keywords

Chrozophora plicata Antioxidant activity Ethanolic extract.

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