Journal: Drug Invention Today

Article Id: JPRS-DFP-00002401
Title: Flavonol glycosides from Azadirachta Indica. L
Category: Drugs from Plants
Section: Research Article
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    Azadirachta indica. L (Meliaceae) is cosmopolitan in distribution and commonly used in several native medical practices. In India, various vegetative parts of A. indica, which includes leaves, flowers, fruits, seeds, and bark, are widely used in Indian traditional medicine for treating various human diseases and disorders. It is also called as storehouse of phytochemicals. The chemical composition is quite complex. Purification, separation, and characterization of few molecules from A. indica (neem) is already reported. In the present study, we report the presence of flavonol glycosides in neem extracts using liquid chromatography and mass spectroscopy spectral analysis. Moreover, for the first time, we report the presence of major flavonol glycosides such as melicitrin (C20 H18 O12 ), quercitrin (C21 H20 O11 ), and rutin (C27 H30 O16 ) from the vegetative parts of A. indica collected from Tirumala Hills, the Eastern Ghats.

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    Author(s) Name:

    Pasupuleti Sreenivasa Rao1,2 *, Gangapatnam. Subramanayam3 , Perali Ramu Sridhar4

    Affiliation(s) Name:

    1 Department of Advanced Research Centre, Narayana Medical College, Nellore, Andhra Pradesh, India,

    2 Department of Pharmacology, Narayana College of Pharmacy, Nellore, Andhra Pradesh, India,

    3 Departments of Cardiology and Advanced Research Centre, Narayana Medical College, Nellore, Andhra Pradesh, India, 4 School of Chemistry, University of Hyderabad, Gachibowli, Hyderabad, Telangana, India

    *Corresponding author: Dr. Pasupuleti Sreenivasa Rao, Department of Advanced Research Centre, Narayana Medical College and Hospitals, Chinthareddypalem, Nellore - 524 002, Andhra Pradesh, India.

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    Author:

    Pasupuleti Sreenivasa Rao1,2 *, Gangapatnam. Subramanayam3 , Perali Ramu Sridhar4

    Title:Flavonol glycosides from Azadirachta Indica. L
    Journal:Drug Invention Today
    Vol(issue):10 (August)
    Year:2018
    Page No: (1421-1426)
  • Experimental Methods Keywords

    Methodology: Liquid chromatography and mass spectroscopy, Natural products, Secondary metabolites
    Research Materials:Azadirachta indica. L

Keywords

Azadirachta indica. L Flavonoids Flavonol glycosides Liquid chromatography and mass spectroscopy Melicitrin (C20 H18 O12 ) Natural products Quercitrin (C21 H20 O11 ) Rutin (C27 H30 O16

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