Journal: Journal of Pharmacy Research

Article Id: JPRS-ND-00002443
Title: Preliminary phytochemical screening and anthelmintic activity of leaves of Indigofera mysorensis Rottler ex DC.
Category: Natural Drugs
Section: Research Article
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    Aim: Helminthic infections are among the most widespread infections in humans, distressing a huge population of the world. The aim of the present study is to investigate the anthelmintic activity of leaves of Indigofera mysorensis using Indian earth worms. Materials and Methods: In the current study, experiments were conducted to evaluate the possible anthelmintic effects of crude acetone, alcohol, aqueous, benzene, chloroform, ethanol, methanol, and petroleum ether extracts of leaves of I. mysorensis using Pheretima posthuma. Various concentrations of 5 and 10 mg/ml of all extracts were tested, and results were expressed in terms of time for paralysis and time of death of worms. Results and Discussion: The acetone extracts (4.06 ± 0.30 min) were more effective followed by ethyl acetate and methanol extracts and almost all the extracts showed better activity than the standard drug Albendazole (10 mg/ml) in taking less time for the paralysis and death of the worms. The preliminary phytochemical screening indicated the presence of alkaloids, phenols, flavonoids, glycosides, and saponins in alcohol, aqueous, chloroform, ethyl acetate, and methanol extracts. Conclusion: The results suggest that different extracts from leaves of I. mysorensis have promising anthelmintic activity and that broadly, this plant extracts are a potential rich source of anthelmintics to cure helminthic diseases.

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    Author(s) Name:

    B. Kavitha*, M. Sonia Rani

    Affiliation(s) Name:

    Department of Botany, Rayalaseema University, Kurnool, Andhra Pradesh, India

    *Corresponding author: B. Kavitha, Department of Botany, Rayalaseema University, Kurnool - 518 007, Andhra Pradesh, India.

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    Author:

    B. Kavitha*, M. Sonia Rani

    Title:Preliminary phytochemical screening and anthelmintic activity of leaves of Indigofera mysorensis Rottler ex DC.
    Journal:Journal of Pharmacy Research
    Vol(issue):12 (June)
    Year:2018
    Page No: (871-874)
  • Experimental Methods Keywords

    Methodology: Anthelmintics,Preliminary screening
    Research Materials:Indigofera mysorensis, Leaves, Pheretima posthuma,

Keywords

Albendazole Anthelmintics Indigofera mysorensis Leaves Pheretima posthuma Preliminary screening

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