Journal: JPR:BioMedRx:An International Journal

Article Id: JPRS-IALI-0000245
Title: Simultaneous estimation of cefixime trihydrate and linezolid in tablet dosage form by derivative spectrophotometric method
Category: Instrumental analysis led to identification
  • Abstract
  • Audio Abstract
  • Authors
  • Pdf File
  • Citation
  • My Reference
  • Methodology
  • Abstract

    Simple, rapid, accurate and precise spectrophotometric method have been developed for simultaneous estimation of Cefixime trihydrate and Linezolid in tablet dosage form. Method involves, formation of ‘1st derivative spectroscopic method’ at 255.3 nm (zeros crossover point of cefixime) and 325.82 nm (zero cross over point of linezolid) using methanol as a solvent. The linearity was observed in the concentration range of 2 - 14 µg /ml for Cefixime trihydrate and 2 - 18 µg/ml for Linezolid. The results of analysis have been validated statistically and by recovery studies and were found satisfactory. Limit of detection for cefixime trihydrate and linezolid were found to be 0.54 µg/ml and 0.77 µg/ml respectively. Limit of quantification for cefixime trihydrate and linezolid were found to be 1.54 µg/ml and 1.67 µg/ml.

  • Abstract Audio

    Click Here

  • About the authors and Affiliations

    Author(s) Name:

    Garaniya Rohini R*, Nisha H. Parikh

    Affiliation(s) Name:

    Arihant School of Pharmacy and Bri, Uvarsad Square, S.G.Highway, Adalaj, Dist.Gandhinagar-382421, Gujarat,India

    *Corresponding author.
    Garaniya Rohini R
    Arihant School of Pharmacy and Bri,
    Uvarsad Square, S.G.Highway,
    Adalaj, Dist.Gandhinagar-382421,
    Gujarat,India.


    Received on:17-09-2012; Revised on: 19-10-2012; Accepted on:10-12-2012

  • View Article File in pdf format.

    Article File
  • View Article Citation Here.

    0 View More
  • How to Cite my Article.

    Author:

    Garaniya Rohini R*, Nisha H. Parikh

    Title:Simultaneous estimation of cefixime trihydrate and linezolid in tablet dosage form by derivative spectrophotometric method
    Journal:JPR:BioMedRx:An International Journal
    Vol(issue):1 (January )
    Year:2013
    Page No: (82-85)
  • Experimental Methods Keywords

    Methodology:Derivative spectroscopy.
    Research Materials:Cefixime Trihydrate, Linezolid,

Keywords

Cefixime Trihydrate Linezolid Derivative spectroscopy.

Our Services

Most Downloaded List