Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002474
Title: Influence of amylase, trypsin and pepsin on the progression of dental erosion
Category: Pharmacology
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    Aim: The gastric and pancreatic enzymes could perhaps degrade the organic matrix of eroded dentine. This study sought to investigate whether pepsin, trypsin, or the amylase have an influence on erosive mineral loss in dentine and whether they are able to degrade the organic matrix. Materials and Methods: The saliva samples were taken from the dental problem facing subjects and the influence of amylase, pepsin, and trypsin enzymes was checked. The enzymes were assayed using standard methods and the absorbance was recorded. Results: The levels of the amylase, pepsin, and trypsin present in saliva of eroded tooth subjects were found to be significantly higher (P < 0.001) than the level of these enzymes in saliva samples from normal individuals. Conclusion: The combined impact of pepsin, amylase, and trypsin increases the dentine erosion. This could be one reason for the fast proceeding of dental erosion in patients with chronic vomiting and ulceritis.

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    Author(s) Name:

    Faazila Fathima1 , V. Vishnu Priya2 *, R. Gayathri 2

    Affiliation(s) Name:

    1 Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: V. Vishnu Priya, Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.

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    Author:

    Faazila Fathima1 , V. Vishnu Priya2 *, R. Gayathri 2

    Title:Influence of amylase, trypsin and pepsin on the progression of dental erosion
    Journal:Drug Invention Today
    Vol(issue):10 (September )
    Year:2018
    Page No: (1737-1739)
  • Experimental Methods Keywords

    Methodology:Dental erosion
    Research Materials:Amylase

Keywords

Amylase Dental erosion Enzymes Pepsin Trypsin

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