Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002543
Title: Comparison of analgesic efficacy between acetaminophen and ibuprofen after circumcision
Category: Pharmacology
Section: Research Article
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    Purpose: The purpose of this study is to compare the analgesic efficacy between acetaminophen and ibuprofen after circumcision. Methods: A quasi-experimental approach was used to compare the analgesic efficacies of acetaminophen and ibuprofen by pain scale scoring and measurement of pain-free duration after administration. Thirty-six male children (5–12 years old) circumcised at Nur Hidayah Hospital, Yogyakarta, Indonesia, who fulfilled the inclusion criteria were included in the study. Half of the subjects were given 180 mg acetaminophen, while the other half received 180 mg ibuprofen after circumcision. The pain scale was scored using a visual analog scale after 1 h of administration. The pain-free duration was determined from administration until the subject felt pain. Results: Ibuprofen treatment was associated with a significantly lower pain level (P < 0.05) and longer pain-free duration (P < 0.05) than acetaminophen treatment after circumcision. Conclusion: Ibuprofen is more effective as an analgesic agent than acetaminophen after circumcision.

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    Author(s) Name:

    Ardi Pramono*, Roosvenda Rahmah Bahardinny

    Affiliation(s) Name:

    Department of Anesthesia and Biochemistry, Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Yogyakarta, Yogyakarta, Indonesia

    *Corresponding author: Ardi Pramono, Department of Anesthesia and Biochemistry, Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Yogyakarta, Yogyakarta, Indonesia

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    Author:

    Ardi Pramono*, Roosvenda Rahmah Bahardinny

    Title:Comparison of analgesic efficacy between acetaminophen and ibuprofen after circumcision
    Journal:Drug Invention Today
    Vol(issue):10 (Oct)
    Year:2018
    Page No: (1996-1998)
  • Experimental Methods Keywords

    Methodology:Analgesic efficacy
    Research Materials:Acetaminophen and ibuprofen

Keywords

Acetaminophen Analgesic efficacy Circumcision Ibuprofen

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