Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002596
Title: Levels of luteinizing hormone in patient with polycystic ovarian syndrome
Category: Pharmacology
Section: Research Article
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    Introduction: The polycystic ovary syndrome (PCOS) could be a disease of feminine sexual sphere that is characterized by the violation of the development of female sexual hormones, increases within the ovary sizes with the appearance of cysts, and impairments of an oscillation, infertility, and alternative symptoms. The luteinizing hormone (LH) could be an endocrine hormone, a regulator of the menstrual cycle, and therefore, the formation of endocrine hormones at ladies, a stimulator of synthesis of testosterone at men LH is made by the pituitary within the brain. Management of gonadotropin production could be an advanced system involving hormones made by the gonads (ovaries or testes), the pituitary, and therefore the hypothalamus. PCOS ladies have an accrued level of gonadotropin and an attenuated level of gonadotropin that ends up in the disorders within the regulation of the menstrual cycle. The aim of the research is to try and do a study on levels of luteinizing hormone within the patients with polycystic ovarian syndrome. Materials and Methods: Patients were selected from those attending the Outpatient Department of Saveetha Dental College and Hospitals and divided into two groups as follows: Group I - Normal healthy individuals - 25 individuals. Group II - Polycystic ovarian syndrome patients - 25 individuals. Inclusion Criteria: The following criteria are included in the study: (1) Individuals with the age group of 20–30 years and (2) PCOS patients. Exclusion Criteria: The following criteria are excluded from the study: (1) Individuals with other systemic illness such as cardiovascular disease, renal failure, stroke, and endocrine illness, (2) individuals with acute illness like fever, and (3) immunocompromised individuals. Sample Collection: Informed consent was obtained from the patient before sample collection. 3 ml of fasting venous blood was collected and distributed in plain collection tubes and centrifuged in 3000 rpm for serum. Then, serum was separated and analyzed to estimate the LH using Robonik Elisa reader. Results: All the data were analyzed using SPSS package. Paired sample t-test analysis was done to find out significant differences between the two groups. All the tests were considered statistically significant at P < 0.05 level. Conclusion: LH is produced by gonadotropic cells present in the anterior pituitary gland. In this survey, we can show that the level of LH in polycystic ovarian disease (PCOD) patients rises 94.033 ± 35.09, whereas the value of LH in normal patients is 5.9 ± 3.5. The LH levels are increased in PCOS patients. From this survey, we get to know the effect of level of LH in PCOD patients.

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    Author(s) Name:

    Sohaib Shahzan1 , A. Jothi Priya2* , Gayatri Devi 2

    Affiliation(s) Name:

    1 Department of Physiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India,

    2 Department of Physiology, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India

    *Corresponding author: A. Jothi Priya, Department of Physiology, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India.

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    Author:

    Sohaib Shahzan1 , A. Jothi Priya2* , Gayatri Devi 2

    Title:Levels of luteinizing hormone in patient with polycystic ovarian syndrome
    Journal:Drug Invention Today
    Vol(issue):10 (Nov)
    Year:2018
    Page No: (2205-2207)
  • Experimental Methods Keywords

    Methodology:Hormone levels, Luteinizing hormone, Polycystic ovarian syndrome
    Research Materials:Females

Keywords

Females Hormones Hormone levels Luteinizing hormone Polycystic ovarian syndrome

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