Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002642
Title: Evaluation of lipid profile status in metabolic syndrome
Category: Pharmacology
Section: Research Article
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    Introduction: Metabolic syndrome (MetS) is known as a group of cardiovascular risk factors associated with insulin resistance, hypertension, glucose intolerance, hypertriglyceridemia, and low levels of high-density lipoprotein cholesterol (HDL-C). It is a major worldwide public health problem. The aim of this study is to analyze the lipid profile status in MetS. Materials and Methods: Healthy individuals and individuals with MetS underwent serum analyzed for fasting blood sugar (FBS) by glucose oxidase-peroxidase method, serum cholesterol by cholesterol esterase-oxidase method, serum triglycerides by colorimetric enzymatic method, HDL-C by phosphotungtic acid method, low-density lipoprotein-cholesterol (LDL-C), and very LDL-C (VLDL-C) were calculated by Friedwald’s formula and lipid profile status was compared between the two groups. Results: All the data were analyzed using the SPSS package. The mean value of FBS, triglyceride level, total cholesterol, HDL-C, LDL-C, and VLDL-C in individuals with MetS was found to be 105 ± 31.22, 151.1 ± 38.80, 191.15 ± 35.12, 20.7 ± 6.31, 140.3 ± 35.37, and 30.42 ± 6.76, respectively. Conclusion: From this study, it is evident that individuals with MetS have most of the risk factors that increase the person’s risk of heart attack and stroke. Aside from the increase in waist circumference, most of the disorders associated with MetS have no symptoms.

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    Author(s) Name:

    A. Shamaa Anjum1 , R. Gayatri Devi 2* , Jothi Priya2 , G. Savitha3

    Affiliation(s) Name:

    1 Department of Physiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Physiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, Tamil Nadu, India,

    3 Department of Biochemistry, Saveetha Dental College and Hospital, SIMATS, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: R. Gayatri Devi, Department of Physiology, Saveetha Dental College, Saveetha University, 162, Poonamallee High Road, Chennai – 600 077, Tamil Nadu, India.

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    Author:

    A. Shamaa Anjum1 , R. Gayatri Devi 2* , Jothi Priya2 , G. Savitha3

    Title:Evaluation of lipid profile status in metabolic syndrome
    Journal:Drug Invention Today
    Vol(issue):10 (December)
    Year:2018
    Page No: (2366-2369)
  • Experimental Methods Keywords

    Methodology:Evaluation of lipid profile status
    Research Materials:Diabetes

Keywords

Diabetes Heart diseases Lipid profile Metabolic syndrome Obesity

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