Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002660
Title: Evaluation of anti-inflammatory action of Illicium verum - An in vitro study
Category: Pharmacology
Section: Research Article
  • Abstract
  • Audio Abstract
  • Authors
  • Pdf File
  • Citation
  • My Reference
  • Methodology
  • Abstract

    Introduction: Illicium verum is a medium-sized evergreen tree native to northeast Vietnam and southwest China. A spice commonly called star anise. Star anise refers to aromatic herbs which are used in cooking for their distinctive flavor and their fragrance. Star anise is the major source of the chemical compound, shikimic acid which is a pharmaceutical synthesis of anti- influenza drug. It also has raw materials needed for fermentation of the food. Star anise has anti-inflammatory, antimicrobial, antifungal, and antioxidant properties. It has many medicinal properties which can also be used to treat cancer as well as gastric problems. It is an easily available herb in the market and is easily affordable by many people; it can be used in the treatment of various diseases. Materials and Methods: The anti-inflammatory activity was studied using protein denaturation assay and the results were read spectrophotometrically. Results: The anti-inflammatory activity of the extract was studied by its ability to inhibit protein denaturation. It was effective in inhibiting heat induced albumin denaturation at different concentrations. Maximum inhibition, 77.87 ± 1.55 was observed at 500 µg/ml. Half-maximal inhibitory concentration value was found to be 105.35 ± 1.99 µg/ml. Conclusion: The result obtained was compared to the commonly available nonsteroidal anti- inflammatory drugs such as aspirin. This research conducted to make the herb worthy for further investigation.

  • Abstract Audio

    No Audio file found

  • About the authors and Affiliations

    Author(s) Name:

    Rachel Paul 1 , R. V. Geetha2 *

    Affiliation(s) Name:

    1 Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: R. V. Geetha, Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.

  • View Article File in pdf format.

    Article File
  • View Article Citation Here.

    0 View More
  • How to Cite my Article.

    Author:

    Rachel Paul 1 , R. V. Geetha2 *

    Title:Evaluation of anti-inflammatory action of Illicium verum - An in vitro study
    Journal:Drug Invention Today
    Vol(issue):10 (December)
    Year:2018
    Page No: (2441-2444)
  • Experimental Methods Keywords

    Methodology:Anti-influenza,Inflammatory, Nonsteroidal anti-inflammatory drug, Shikimic acid, Star anise
    Research Materials: Illicium verum

Keywords

Anti-influenza Illicium vernum Inflammatory Nonsteroidal anti-inflammatory drug Shikimic acid Star anise

Our Services

Most Downloaded List