Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002672
Title: In vitro evaluation of anti-biofilm activity of Orange peel extract on Streptococcus mutans
Category: Pharmacology
Section: Research Article
  • Abstract
  • Audio Abstract
  • Authors
  • Pdf File
  • Citation
  • My Reference
  • Methodology
  • Abstract

    Introduction: Biofilm inhibition is considered as major drug target for the treatment of various bacterial and fungal infections, and so the pharmacological development of drugs is now extensively studied in all the parts of the world. Citrus sinensis is the widely grown crop which is easily available all over the world. The various medicinal properties of the orange peel extract such as action against colic, upset stomach, cancer, diuretic, cormunative, immune-enhancing, and skin has been listed. It can also be used to treat and prevent vitamin deficiencies, colds, flu, and scurvy and also contain antibacterial and antiviral activities. The aim of the present study is to evaluate the in vitro anti-biofilm activity of orange peel extract on Streptococcus mutants. Materials and Methods: The S. mutans which are obtained from the saliva samples are been treated with orange peel extract which is been commercially obtained from the markets. The inhibitory action of orange peel extract on biofilm formation by S. mutans was quantified by in vitro study using microtiter plate assay. Results: After incubation, the results are recorded spectrophotometrically, the extract showed 85.49% activity at concentration of 100 µg/ml. Conclusion: The inhibition activity of the orange extract on the S. mutans was significantly high. Hence, we can suggest that use of higher concentration of the orange extract will totally inhibit the activity of the S. mutans.

  • Abstract Audio

    No Audio file found

  • About the authors and Affiliations

    Author(s) Name:

    S. Vignesh, R. V. Geetha*

    Affiliation(s) Name:

    Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: R. V. Geetha, Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai – 600 077, Tamil Nadu, India.

  • View Article File in pdf format.

    Article File
  • View Article Citation Here.

    0 View More
  • How to Cite my Article.

    Author:

    S. Vignesh, R. V. Geetha*

    Title:In vitro evaluation of anti-biofilm activity of Orange peel extract on Streptococcus mutans
    Journal:Drug Invention Today
    Vol(issue):10 (December)
    Year:2018
    Page No: (2485-2488)
  • Experimental Methods Keywords

    Methodology: Anti-biofilm activity, concentration, Streptococcus mutans
    Research Materials:Citrus sinensis peels

Keywords

Anti-biofilm activity caries Citrus sinensis peels concentration Streptococcus mutans

Our Services

Most Downloaded List