Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002690
Title: The effectiveness of the combined use of a polysaccharide film with photodynamic action in complex therapy of oral lichen planus in the oral cavity
Category: Pharmacology
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    Aim: Oral lichen planus (OLP) is a chronic, multifocal, and sometimes painful, inflammatory disease of the oral mucosa. OLP can predispose the development of psychoemotional disorders. This study aimed to examine the cases of complex treatment of OLP, a description of the use of self-absorbing plates based on natural polysaccharides in combination with phototherapy in the treatment of OLP. Materials and Methods: It was used apparatus for phototherapy Dune-T with LEDs generating radiation: red wavelength - 632.7 nm (radiation density - 0.8 mW/cm2 ) and infrared - 840 nm (radiation density - 1.5 mW/cm2 ). 40 patients aged 30 to 66 years, women 26 (65%), men 14 (35%) were under observation. The highest incidence of this form of CRP occurred at age 50 to 59 years (15 patients, 37.5%). Equally often (10 patients, 25%), this nosology was observed in the age intervals 40-49 and 60 years or more. In all age groups, women suffered more often than males. It should be noted that in 23 patients (57.5%) the disease was diagnosed for the first time. Results and Discussion: All patients with OLP noted that in the oral cavity on the mucous membrane of the retromolar space and cheeks in the molar region before the appearance of painful erosions, whitish with a pearly hue pattern was defined that resembled the pattern of fern leaves, spider webs or lace. Conclusions: Thus, the conducted research allows us to recommend a combined application of the apparatus for phototherapy with the subsequent application of a polysaccharide film, which significantly reduces pain in patients, and also reduces the number of days of treatment.

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    Author(s) Name:

    Zarina Paiziyeva1 *, Alina Puriene2

    Affiliation(s) Name:

    1 Department of Dentistry and Maxillofacial Surgery, JSC Astana Medical University, The Republic of Kazakhstan, Beibitshilik str., 49A, Astana 010001, Kazakhstan,

    2 Department of Dentistry and Maxillofacial Surgery, Institute of Odontology, Faculty of Medicine,Vilnius University, Universiteto str. Nr.3, 01131 Vilnius, Lithuania

    *Corresponding author: Zarina Paiziyeva, Department of Dentistry and Maxillofacial Surgery, JSC Astana Medical University, The Republic of Kazakhstan, Aray str., 29/2, Astana 010001, Kazakhstan

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    Author:

    Zarina Paiziyeva1 *, Alina Puriene2

    Title:The effectiveness of the combined use of a polysaccharide film with photodynamic action in complex therapy of oral lichen planus in the oral cavity
    Journal:Drug Invention Today
    Vol(issue):10 (December)
    Year:2018
    Page No: (2553-2559)
  • Experimental Methods Keywords

    Methodology:Oral cavity dermatosis, Oral lichen planus, Oral mucosa, Phototherapy, Self-absorbing plates
    Research Materials:Polysaccharide film

Keywords

Oral cavity dermatosis Oral lichen planus Oral mucosa Phototherapy Self-absorbing plates

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