Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002693
Title: The effect of solvents and extraction time on total xanthone and antioxidant yields of mangosteen peel (Garcinia mangostana L.) extract
Category: Pharmacology
Section: Research Article
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  • Abstract

    This study aims to evaluate the effect of different solvents and extraction time on total xanthone and antioxidant yield of mangosteen peel extract. The research was conducted by extracting mangosteen peel using seven solvents: Ethanol, acetone, ethyl acetate, methanol, hexane, acetic acid, and aquadest at different times: 24, 36, and 48 h. Total xanthone was examined using visible UV spectrophotometer at the particular wavelength, and antioxidant yield was observed from the extract and then dried using rotary evaporator and freeze dryer. The result reported that the solvents and extraction time significantly (P < 0.01) affected total xanthone and antioxidant yield. Mangosteen peel extracted by acetone shows the best results on total xanthone at 48 h. Meanwhile, mangosteen peel extracted by ethanol for 24 h was the best result on antioxidant yield. Total xanthone levels and antioxidant yield are affected by solvents and extraction time. Total xanthone levels were best found at long extraction times, while the best levels of antioxidant yield were found at short extraction times. Acetone and ethanol solvents which have medium polarity index (5.1 and 5.2, respectively) show the highest levels of total xanthone and best antioxidant yield compared to other treatments.

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    Author(s) Name:

    Andri Kusmayadi 1,2 *, Lovita Adriani 1 , Abun Abun1 , Muchtaridi Muchtaridi 3 , Ujang Hidayat Tanuwiria1

    Affiliation(s) Name:

    1 Department of Animal Science, Faculty of Animal Science, Universitas Padjadjaran, Sumedang-45363, Indonesia,

    2 Department of Animal Science, Faculty of Agriculture, Universitas Perjuangan, Tasikmalaya-46115, Indonesia,

    3 Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang-45363, Indonesia

    *Corresponding author: Andri Kusmayadi, Faculty of Animal Science, Universitas Padjadjaran, Bandung – Sumedang KM. 21. Jatinangor, Sumedang, Indonesia.

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    Author:

    Andri Kusmayadi 1,2 *, Lovita Adriani 1 , Abun Abun1 , Muchtaridi Muchtaridi 3 , Ujang Hidayat Tanuwiria1

    Title:The effect of solvents and extraction time on total xanthone and antioxidant yields of mangosteen peel (Garcinia mangostana L.) extract
    Journal:Drug Invention Today
    Vol(issue):10 (December)
    Year:2018
    Page No: (2572-2576)
  • Experimental Methods Keywords

    Methodology:UV spectrophotometer , rotary evaporator, freeze dryer
    Research Materials:Mangosteen peel (Garcinia mangostana L.)

Keywords

Antioxidant yield Mangosteen peel extract Solvent Extraction Time Total Xanthone

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